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Statistics from ISRCTN Register
Notes:
- All the information is as of June 2012.
- Figures given below represent the number of trials added to the ISRCTN Register or ClinicalTrials.gov per year or per month, not the number of trials started or taking place at any particular moment in time.
- Study domains represented in ISRCTN register: the ISRCTN disease classification is loosely based on the WHO ICD10 chapters and intends to give a broad indication of which study domains trials belong to.
- UK related trials included in UK Clinical Trials Gateway (UKCTG): the UKCTG brings together trials that are recruiting or have recruited participants from the UK, using 2 sources: ISRCTN.org and Clinical.Trials.gov.
- Top countries registering trials with ISRCTN IDs: country is defined as the country where the sponsor of the trial is based. The sponsor is defined as the organisation taking legal responsibility for the trial.
Disclaimer:
Public trial registration is not legally mandated in most countries. As a result, the ISRCTN register is not comprehensive and does not claim to give an exact picture of all clinical trials taking place in the UK or in any other country listed below. Increases or decreases in the number of trials registered do not necessarily imply that more or fewer trials take place in specific years.
Study domains |
Studies by disease type in the ISRCTN Register, June 2012 |
Study domain |
2000 |
2001 |
2002 |
2003 |
2004 |
2005 |
2006 |
2007 |
2008 |
2009 |
2010 |
2011 |
2012 |
Total |
Cancer |
54 |
128 |
148 |
59 |
70 |
157 |
139 |
117 |
95 |
89 |
144 |
129 |
59 |
1,388 |
Cardiovascular |
10 |
8 |
23 |
77 |
110 |
169 |
143 |
122 |
101 |
72 |
126 |
83 |
44 |
1,088 |
Digestive System |
|
6 |
3 |
42 |
41 |
50 |
42 |
45 |
45 |
30 |
46 |
24 |
15 |
389 |
Ear, Nose and Throat |
1 |
|
1 |
9 |
15 |
5 |
9 |
11 |
4 |
4 |
2 |
5 |
6 |
72 |
Eye Diseases |
3 |
1 |
1 |
9 |
16 |
29 |
27 |
39 |
27 |
21 |
24 |
9 |
4 |
210 |
Haematological Disorders |
1 |
1 |
1 |
8 |
7 |
12 |
12 |
11 |
11 |
10 |
10 |
18 |
8 |
110 |
Infections and Infestations |
12 |
5 |
6 |
15 |
36 |
122 |
112 |
86 |
98 |
72 |
57 |
52 |
33 |
706 |
Injury, Occupational Diseases, Poisoning |
1 |
|
4 |
14 |
43 |
44 |
35 |
35 |
29 |
39 |
29 |
30 |
16 |
319 |
Mental and Behavioural Disorders |
7 |
4 |
13 |
59 |
104 |
152 |
132 |
136 |
106 |
96 |
152 |
131 |
80 |
1,172 |
Musculoskeletal Diseases |
9 |
10 |
46 |
70 |
63 |
93 |
108 |
118 |
72 |
52 |
83 |
75 |
40 |
839 |
Neonatal Diseases |
2 |
|
|
6 |
23 |
22 |
17 |
10 |
6 |
4 |
10 |
5 |
3 |
108 |
Nervous System Diseases |
6 |
2 |
11 |
22 |
38 |
59 |
52 |
44 |
45 |
41 |
33 |
35 |
17 |
405 |
Not Applicable |
6 |
4 |
5 |
11 |
78 |
35 |
33 |
35 |
24 |
48 |
45 |
37 |
30 |
391 |
Nutritional, Metabolic, Endocrine |
2 |
6 |
11 |
30 |
48 |
105 |
118 |
122 |
55 |
69 |
127 |
98 |
53 |
844 |
Oral Health |
2 |
2 |
2 |
15 |
29 |
29 |
17 |
14 |
16 |
8 |
13 |
4 |
12 |
163 |
Pregnancy and Childbirth |
9 |
2 |
10 |
34 |
75 |
67 |
43 |
60 |
41 |
44 |
37 |
40 |
22 |
484 |
Respiratory |
7 |
1 |
6 |
35 |
58 |
79 |
62 |
37 |
41 |
54 |
61 |
41 |
20 |
502 |
Signs and Symptoms |
1 |
2 |
5 |
49 |
45 |
64 |
37 |
46 |
25 |
16 |
36 |
6 |
10 |
342 |
Skin and Connective Tissue Diseases |
|
|
1 |
16 |
18 |
22 |
19 |
16 |
11 |
8 |
16 |
5 |
5 |
137 |
Surgery |
3 |
3 |
2 |
118 |
107 |
121 |
88 |
69 |
24 |
39 |
48 |
32 |
18 |
672 |
Urological and Genital Diseases |
9 |
2 |
3 |
31 |
41 |
57 |
59 |
47 |
32 |
20 |
47 |
30 |
12 |
390 |
Grand Total |
145 |
187 |
302 |
729 |
1,065 |
1,493 |
1,304 |
1,220 |
908 |
836 |
1,146 |
889 |
507 |
10,731 |
UK related trials in UK Clinical Trials Gateway |
Proportions of the UKCTG populated from the ISRCTN Register & ClinicalTrials.gov |
End of |
From ISRCTN.org |
From Clinical.Trials.gov |
Total records |
Nov-11 |
5,599 |
6,039 |
11,638 |
Dec-11 |
5,629 |
6,134 |
11,763 |
Jan-12 |
5,682 |
6,259 |
11,941 |
Feb-12 |
5,721 |
6,305 |
12,026 |
Mar-12 |
5,768 |
6,457 |
12,225 |
Apr-12 |
5,803 |
6,507 |
12,310 |
May-12 |
5,866 |
6,657 |
12,523 |
Jun-12 |
5,902 |
6,740 |
12,642 |
Top countries |
Top countries submitting to the ISRCTN Register, 2000 - 2012 |
Country |
2000 |
2001 |
2002 |
2003 |
2004 |
2005 |
2006 |
2007 |
2008 |
2009 |
2010 |
2011 |
2012 |
Total |
United Kingdom |
145 |
183 |
228 |
677 |
923 |
675 |
552 |
507 |
372 |
378 |
608 |
438 |
276 |
5962 |
Netherlands |
|
|
3 |
4 |
17 |
356 |
348 |
239 |
33 |
37 |
50 |
43 |
20 |
1150 |
Germany |
|
|
3 |
15 |
15 |
76 |
73 |
97 |
92 |
83 |
68 |
64 |
30 |
616 |
Canada |
|
1 |
9 |
6 |
16 |
138 |
45 |
54 |
55 |
29 |
27 |
11 |
10 |
401 |
Switzerland |
|
|
2 |
3 |
28 |
45 |
44 |
39 |
33 |
27 |
35 |
41 |
14 |
311 |
United States of America |
|
|
9 |
10 |
16 |
50 |
44 |
20 |
32 |
24 |
28 |
22 |
11 |
266 |
Spain |
|
|
|
|
3 |
13 |
23 |
19 |
26 |
30 |
40 |
25 |
12 |
191 |
Sweden |
|
|
|
1 |
1 |
4 |
12 |
22 |
30 |
23 |
21 |
26 |
14 |
154 |
Italy |
|
|
3 |
1 |
6 |
9 |
9 |
18 |
18 |
29 |
29 |
21 |
10 |
153 |
France |
|
|
1 |
1 |
1 |
8 |
18 |
18 |
29 |
16 |
24 |
24 |
8 |
148 |
Australia |
|
1 |
4 |
8 |
13 |
36 |
13 |
17 |
12 |
8 |
17 |
6 |
3 |
138 |
Belgium |
|
|
4 |
|
2 |
8 |
9 |
10 |
22 |
13 |
15 |
10 |
4 |
97 |
Brazil |
|
|
1 |
|
1 |
2 |
11 |
9 |
20 |
8 |
15 |
14 |
8 |
89 |
China |
|
|
|
|
|
3 |
8 |
15 |
14 |
8 |
17 |
15 |
6 |
86 |
Denmark |
|
|
2 |
|
3 |
4 |
7 |
10 |
4 |
7 |
17 |
14 |
10 |
78 |
Ireland |
|
|
|
|
|
1 |
1 |
6 |
12 |
14 |
16 |
14 |
8 |
72 |
Finland |
|
|
1 |
|
2 |
3 |
11 |
11 |
9 |
10 |
13 |
8 |
3 |
71 |
India |
|
|
1 |
|
1 |
9 |
9 |
14 |
12 |
1 |
9 |
|
2 |
58 |
Norway |
|
|
1 |
1 |
|
4 |
7 |
15 |
8 |
1 |
3 |
7 |
2 |
49 |
Korea, South |
|
|
|
|
|
|
|
6 |
10 |
8 |
10 |
5 |
2 |
41 |
REST OF WORLD |
0 |
2 |
30 |
2 |
17 |
49 |
60 |
74 |
65 |
82 |
84 |
81 |
54 |
600 |
TOTAL |
145 |
187 |
302 |
729 |
1065 |
1493 |
1304 |
1220 |
908 |
836 |
1146 |
889 |
507 |
10731 |
17 October 2012
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