| Source of record | UK Clinical Trials Gateway |
| ISRCTN | ISRCTN46552426 |
| Date ISRCTN assigned | 19/08/2002 |
| Local reference number(s) | BR08 |
| Public title | Medical Research Council Trial of Immediate versus Deferred Treatment for Intracerebral Brain Tumours Presenting With Epilepsy |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Brain and Nervous System |
| Study hypothesis | Not provided at time of registration. |
| Design/methodology | Randomised controlled trial. |
| Research ethics review | Not provided at time of registration. |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Patients with a clinically definite history of epilepsy who have Computed Tomography (CT) and/or Magnetic Resonance (MR) imaging supporting a probable diagnosis of intracerebral tumour
2. Clinical picture, CT or MR imaging is unequivocal and allows exclusion of cerebral abscess or extra-axial tumour (meningioma)
3. No other medical condition likely to effect the feasibility of follow-up
4. No previous neurosurgery, radiotherapy or chemotherapy
5. No other previous or concurrent malignant disease, except non melanomatous carcinoma of the skin
6. Age >16 |
| Participants - exclusion criteria | Not provided at time of registration. |
| Patient information material |
|
| Anticipated start date | 01/12/1988 |
| Anticipated end date | 10/12/1993 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration. |
| Interventions | 1. Group A: Immediate treatment with clinicians choice of one or more of surgery, radiotherapy or chemotherapy, plus best medical treatment
2. Group B: Deferred treatment, with best medical treatment only until intervention becomes clinically necessary |
| Primary outcome measure(s) | Not provided at time of registration. |
| Secondary outcome measure(s) | Not provided at time of registration. |
| Sources of funding | Medical Research Council (UK) |
| Sponsor name | Medical Research Council (UK) |
| Sponsor details | 20 Park Crescent
London
United Kingdom
W1B 1AL |
| Sponsor telephone | +44 (0)20 7636 5422 |
| Sponsor fax | +44 (0)20 7436 6179 |
| Sponsor email | clinical.trial@headoffice.mrc.ac.uk |
| Sponsor website | http://www.mrc.ac.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN46552426 |
| Date last extracted from ISRCTN register | 17/04/2008 |
