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A Prospective-Study of the Effects of Prolonged Timolol Therapy on Alpha-Adrenoceptor and Beta-Adrenoceptor and Angiotensin-II Receptor-Mediated Responses in Normal Subjects
Source of recordUK Clinical Trials Gateway
ISRCTNISRCTN76842657
Date ISRCTN assigned23/01/2004
Local reference number(s)N/A
Public titleA Prospective-Study of the Effects of Prolonged Timolol Therapy on Alpha-Adrenoceptor and Beta-Adrenoceptor and Angiotensin-II Receptor-Mediated Responses in Normal Subjects
Scientific title
AcronymN/A
Disease/condition/study domainCardiovascular diseases: Heart disease; Cardiovascular diseases: Hypertension
Study hypothesisNot provided at time of registration
Design/methodologyRandomised controlled trial
Research ethics reviewNot provided at time of registration
Countries of trialUnited Kingdom
Participants - inclusion criteriaHealthy males
Participants - exclusion criteriaNot provided at time of registration
Patient information material
Status of trialCompleted
Target number of participantsNot provided at time of registration
InterventionsTimolol 10 mg twice daily or placebo for 14 days
Primary outcome measure(s)Not provided at time of registration
Secondary outcome measure(s)Not provided at time of registration
Sources of fundingNHS Executive Eastern
Sponsor nameNHS R&D Regional Programme Register - Department of Health (UK)
Sponsor detailsThe Department of Health
Richmond House
79 Whitehall
London
United Kingdom
SW1A 2NL
Sponsor telephone+44 (0)20 7307 2622
Sponsor fax+44 (0)20 7307 2623
Sponsor emaildhmail@doh.gsi.org.uk
Sponsor websitehttp://www.doh.gov.uk
Contact nameDr A Ferro
Contact detailsUniversity of Cambridge
Department of Medicine
Clinical Pharmacology Unit


Cambridge
United Kingdom
CB2 2QQ
Contact telephone+44
Contact fax+44
More informationFor more up-to-date information please go to the ISRCTN link below.
Link to record in ISRCTN RegisterISRCTN76842657
Date last extracted from ISRCTN register17/04/2008
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