| Source of record | UK Clinical Trials Gateway |
| ISRCTN | ISRCTN17465143 |
| Date ISRCTN assigned | 23/01/2004 |
| Local reference number(s) | MC7 |
| Public title | Ultra low dose anticoagulation in atrial fibrillation |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Cardiovascular diseases: Heart disease |
| Study hypothesis | Previous studies have demonstrated increased markers of thrombogenesis in patients with atrial fibrillation (AF), suggesting the presence of a hypercoaguable or prothromobotic state. The objective of this study was to determine the effects of introducing ultra-low-dose warfarin (1 mg), conventional warfarin, and aspirin (300 mg) therapy on thrombogenesis and platelet activation in AF. |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | Patients with atrial fibrillation |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated start date | 01/04/1994 |
| Anticipated end date | 01/04/1996 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Not provided at time of registration |
| Primary outcome measure(s) | Platelet activation |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | NHS Cardiovascular Disease and Stroke National Research and Development Programme |
| Sponsor name | Record Provided by the NHS R&D 'Time-Limited' National Programme Register - Department of Health (UK) |
| Sponsor details | The Department of Health
Richmond House
79 Whitehall
London
United Kingdom
SW1A 2NL |
| Sponsor telephone | +44 (0)20 7307 2622 |
| Sponsor fax | +44 (0)20 7307 2623 |
| Sponsor email | dhmail@doh.gsi.org.uk |
| Sponsor website | http://www.doh.gov.uk |
| Contact name | Prof Gareth Beevers |
| Contact details | University Department of Medicine
City Hospital
Dudley Rd
Birmingham
United Kingdom
B18 7QH |
| Contact telephone | +44 (0)121 507 5080 |
| Contact email | D.G.BEEVERS@bham.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN17465143 |
| Date last extracted from ISRCTN register | 17/04/2008 |
