| Source of record | UK Clinical Trials Gateway |
| ISRCTN | ISRCTN37445539 |
| Date ISRCTN assigned | 23/08/2000 |
| Local reference number(s) | G9403190 |
| Public title | United Kingdom Pacing And Cardiovascular Events study |
| Scientific title |
|
| Acronym | UKPACE |
| Disease/condition/study domain | Atrioventricular conduction block |
| Study hypothesis | Prospective assessment of single vs. dual chamber pacing in elderly patients with atrioventricular conduction block |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Age greater than 70 years
2. Advanced atrioventricular (A-V) block |
| Participants - exclusion criteria | If survival expected to be less than 1year or totally immobile or confused |
| Patient information material |
|
| Anticipated start date | 01/02/1996 |
| Anticipated end date | 31/03/2003 |
| Status of trial | Completed |
| Target number of participants | 2000 |
| Interventions | Single/dual chamber pacing in elderly patients |
| Primary outcome measure(s) | Primary end point:
1. All cause mortality
2. Outcome measures
3. Quality of Life
4. Cardiovascular Events
5. Cost Utility |
| Secondary outcome measure(s) | Not provided at time of registration |
| Publications | Results: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&list_uids=16014884 |
| Sources of funding | Medical Research Council (UK) |
| Sponsor name | Medical Research Council (UK) |
| Sponsor details | 20 Park Crescent
London
United Kingdom
W1B 1AL |
| Sponsor telephone | +44 (0)20 7636 5422 |
| Sponsor fax | +44 (0)20 7436 6179 |
| Sponsor email | clinical.trial@headoffice.mrc.ac.uk |
| Sponsor website | http://www.mrc.ac.uk |
| Contact name | Dr JD Skehan |
| Contact details | Department of Cardiology
Glenfield NHS Trust
Groby Road
Leicester
United Kingdom
LE3 9QP |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN37445539 |
| Date last extracted from ISRCTN register | 17/04/2008 |
