| Source of record | National Research Register |
| Serial number at source | N0116069211 |
| Project title | Second immunoglobulin dose Guillain-Barre syndrome trial |
| Current status of trial | Complete |
| Main research question | Does a second imunoglobulin course offer a clinically important advantage over a single course in patients who are still severely affected with Guillain Barre syndrome 2 weeks after the start of the first course? |
| Design/methodology | Randomised double blind placebo controlled trial. |
| Sample group description | 250 , 125 in each arm |
| Multi-centre trial? | This is not a multi-centre trial. |
| Outcome measure | 7 point disability and 5 point arm scales, time from randomisation to final cessation of artificial ventilation, time to recover the ability to walk unaided, time to discharge, time to return to previous occupation. |
| Start date | 06/01/2000 |
| End date | 06/01/2002 |
| Primary keywords | POLYRADICULONEURITIS Q-drug-therapy; IMMUNOGLOBULINS Q-administration-&-dosage |
| Secondary keywords | HUMAN; CLINICAL-TRIAL; RANDOMIZED-CONTROLLED-TRIAL; DOUBLE-BLIND-METHOD; PLACEBO-EFFECT |
| Region | London Regional Office |
| NRR Data Provider | Kings College Hospital NHS Trust R&D Consortium |
| Funding organisation: name 1 | National Institute of Health (USA) |
Funding amount 1
[in £ unless otherwise stated] | 10000 |
| Contact name(s) | Professor RAC Hughes |
| Contact details | Section of Neurology
Department of Clinical Neurosciences
GKT School of Medicine
Hodgkin Building, Guy's Hospital
London
SE1 9RT
London
Tel: 020 7955 4398
Fax: 020 7378 1221
Email: r.hughes@umds.ac.uk |
| Further information | This record was taken from the National Research Register 2003, Issue 1, published in February 2003. Further information about this trial can be obtained from the lead researcher named above. |
| Date live in mRCT | 6 February 2003 |
