| Source of record | UK Trials |
| ISRCTN | ISRCTN45684820 |
| Date ISRCTN assigned | 26/02/2008 |
| Local reference number(s) | 04/016 |
| Public title | Does giving advice on avoiding allergies and triggers improve asthma control? A research trial |
| Scientific title | Does structured advice on Allergy and Allergen Avoidance given by practice nurses improve control of asthma in primary care? A single blind randomised controlled trial |
| Acronym | AAA |
| Disease/condition/study domain | Asthma |
| Study hypothesis | The control of asthma can be improved by a structured allergy assessment followed by individualised avoidance advice, given by practice nurses in primary care. |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Ethics approval received from Bristol South NHS Ethics Committee on the 15th November 2004. |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Diagnosis of asthma, confirmed by 20% peak expiratory flow [PEF] diurnal variation in medical records or 15% reversibility on spirometry (British Thoracic Society [BTS]/Scottish Intercollegiate Guidelines Network [SIGN] 2003)
2. Prescribed asthma medication within the past year
3. Aged between 16 to 55 years, either sex
4. Not had skin prick testing in the past 10 years |
| Participants - exclusion criteria | Unable to give informed consent. |
| Patient information material |
|
| Anticipated start date | 01/01/2005 |
| Anticipated end date | 01/01/2006 |
| Status of trial | Completed |
| Target number of participants | 200 |
| Interventions | Control patients:
Usual care asthma reviews (UC) consisted of assessment of symptoms, inhaler technique, and medication usage, and provision of self-management action plans.
Intervention patients:
Structured allergen and trigger avoidance advice reviews (AAA) comprised the elements of a usual review as above, supplemented by a structured asthma and allergy assessment consisting of:
1. Skin prick testing
2. Completion of the Structured Allergy Questionnaire and Asthma Trigger Inventory
3. Avoidance advice for identified triggers
Duration of these was about 30 - 45 minutes. There was no further contact with the nurse until follow up 4 months later. |
| Primary outcome measure(s) | Lung function/symptoms, assessed at 4 months. |
| Secondary outcome measure(s) | Self efficacy, assessed at 4 months. |
| Sources of funding | Asthma UK (UK) (ref: 04/016) |
| Sponsor name | St George's Hospital Medical School (UK) |
| Sponsor details | Cranmer Terrace
London
United Kingdom
SW17 0RE |
| Sponsor website | http://www.sgul.ac.uk/ |
| Contact name | Prof Chris Griffiths |
| Contact details | Centre for Health Sciences
Barts and the London Medical School
2 Newark st
London
United Kingdom
E1 4NS |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN45684820 |
| Date last extracted from ISRCTN register | 17/04/2008 |
