| Source of record | UK Trials |
| ISRCTN | ISRCTN43319045 |
| Date ISRCTN assigned | 22/06/2006 |
| Local reference number(s) | N/A |
| Public title | The nutritional, cardiovascular and immunological effect of daily subcutaneous ghrelin in dialysis patients with evidence of malnutrition |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Malnutrition or renal failure |
| Study hypothesis | Ghrelin treatment has beneficial effects on the disordered nutritional, cardiovascular and immunological physiology of dialysis patients. |
| Design/methodology | Randomised, double-blind, placebo-controlled, crossover trial |
| Research ethics review | Approved by the Riverside Research Ethics Committee on 01/02/2006, reference number: 05/Q0401/132 |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | Dialysis patients at West London Renal and Transplant Centre, Hammersmith Hospital with evidence of malnutrition |
| Participants - exclusion criteria | 1. Anaemia
2. Over 75 years of age
3. Recent illness |
| Patient information material |
|
| Anticipated start date | 13/03/2006 |
| Anticipated end date | 01/12/2006 |
| Status of trial | Completed |
| Target number of participants | 20 |
| Interventions | Subcutaneous ghrelin versus placebo |
| Primary outcome measure(s) | 1. Blood pressure
2. Energy expenditure
3. Cytokine production |
| Secondary outcome measure(s) | 1. Food intake
2. Nutritional parameters |
| Sources of funding | Hammersmith Hospital NHS Trust (UK) |
| Sponsor name | Hammersmith Hospitals NHS Trust (UK) |
| Sponsor details | Du Cane Road
London
United Kingdom
W12 0HS |
| Sponsor website | http://www.hhnt.org/trust/index.htm |
| Contact name | Dr Peter Choi |
| Contact details | West London Renal and Transplant Centre
Hammersmith Hospital
Du Cane Road
London
United Kingdom
W12 0HS |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN43319045 |
| Date last extracted from ISRCTN register | 17/04/2008 |
