| Source of record | UK Trials |
| ISRCTN | ISRCTN83441783 |
| Date ISRCTN assigned | 19/08/2002 |
| Local reference number(s) | UKHAP2 |
| Public title | UK Hepatic Artery Pump Trial Two: Continuous Hepatic-Artery Infusion for Palliation in Colorectal Liver Metastases |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Colon, Liver, Rectum |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Aged <75 years
2. Colorectal liver metastases, less than 45% liver involvement as assessed by Computed Tomography (CT) scan
3. Karnofsky score more than 80%
4. Normal Billirubin level
5. No prior chemotherapy |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated end date | 01/09/1996 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | 1. Regimen A: Intra-hepatic continuous infusion of floxuridine for 5 days followed by systemic 5-fluorouracil and folinic acid for 5 days delivered via an arterial port-a-cath.
2. Regimen B: Systemic 5-fluorouracil and folinic acid for 5 days delivered via an arterial port-a-cath. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Colon Cancer Concern |
| Sponsor name | Colon Cancer Concern |
| Sponsor details | 9 Rickett Street
London
United Kingdom
SW6 1RU |
| Sponsor telephone | +44(0)020 7381 9711 |
| Sponsor fax | +44(0)020 7381 5752 |
| Sponsor email | queries@coloncancer.org.uk |
| Sponsor website | http://www.coloncancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN83441783 |
| Date last extracted from ISRCTN register | 17/04/2008 |
