| Source of record | UK Trials |
| ISRCTN | ISRCTN43344383 |
| Date ISRCTN assigned | 19/08/2002 |
| Local reference number(s) | LK/FIL |
| Public title | A Study of the Prevention of Alloimmunisation using Leukocyte-Depleted Red Cell and Platelet Donations |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Leukaemia (acute), Leukaemia (chronic) |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Patients with acute leukaemia, chronic myeloid leukaemia, severe aplastic anaemia or high grade lymphoma
2. Patients already known to have Human Leukocyte Antigens (HLA) antibodies or recurrent febrile transfusion reactions are ineligible
3. Any age
4. Fit to undergo the treatments as defined in protocol |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated end date | 01/04/1992 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Patients are randomised to one of two treatment arms:
1. Arm A: Patients receive standard non-filtered, non-leukocyte-depleted blood products.
2. Arm B: Patients receive Pall filtered blood or platelet donations. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Pall Biomedical Ltd |
| Sponsor name | Pall Biomedical Ltd |
| Sponsor details |
Portsmouth
United Kingdom
|
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN43344383 |
| Date last extracted from ISRCTN register | 17/04/2008 |
