| Source of record | UK Clinical Trials Gateway |
| ISRCTN | ISRCTN83218866 |
| Date ISRCTN assigned | 19/08/2002 |
| Local reference number(s) | ILT-2 |
| Public title | A Randomised Trial Comparing External Beam Radiotherapy Alone With External Beam Radiotherapy Plus Intraluminal Irradiation for Palliation in Lung Cancer |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Lung (non-small cell) |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Biopsy proven non-small cell lung cancer
2. Fit to receive bronchoscopy
3. Fit to receive external beam radiotherapy
4. Any age
5. Shortness of breath, cough, haemoptysis, dysphagia or chest pain resulting from a primary bronchial tumour
6. No previous or concomitant malignancy, except basal cell carcinomas
7. No symptomatic metastases requiring external beam radiotherapy
8. No previous chest irradiation for lung cancer
9. No bilateral lung tumours or tracheal tumours |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | 1. Schedule A: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour.
2. Schedule B: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour. Followed by intraluminal radiotherapy, a single dose of 1500 cGy to be given on the last day of external beam radiotherapy. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Not available |
| Sponsor name | UK Co-ordinating Committee for Cancer Research (UKCCCR) |
| Sponsor details | MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Sponsor telephone | +44 (0) 20 7670 4723 |
| Sponsor fax | +44 (0) 20 7670 4818 |
| Sponsor email | register@ctu.mrc.ac.uk |
| Sponsor website | http://www.ctu.mrc.ac.uk/ukcccr/home.html |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN83218866 |
| Date last extracted from ISRCTN register | 17/04/2008 |
