| Source of record | UK Trials |
| ISRCTN | ISRCTN92341395 |
| Date ISRCTN assigned | 19/08/2002 |
| Local reference number(s) | CRBT |
| Public title | A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Colon, Rectum |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Patients undergoing elective resection of colorectal carcinoma
2. No transfusion of blood in the 6 months preceding the operation
3. No transfusion of blood prior to the first postoperative sample
4. No concurrent immunosuppressive medication
5. No previous transfusion reaction requiring cessation of transfusion |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Patients are randomised to one of three treatment arms:
1. Arm A: Surgery without transfusion
2. Arm B: Surgery with standard blood transfusion
3. Arm C: Surgery with leucodepleted blood transfusion |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Leicester General Hospital |
| Sponsor name | Leicester General Hospital |
| Sponsor details | Gwendolen Road
Leicester
United Kingdom
LE5 4PW |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN92341395 |
| Date last extracted from ISRCTN register | 17/04/2008 |
