| Source of record | UK Trials |
| ISRCTN | ISRCTN41186152 |
| Date ISRCTN assigned | 08/03/2002 |
| Local reference number(s) | PG/02/024 |
| Public title | Randomised, placebo controlled study of the effect of sildenafil on hypoxia-induced pulmonary hypertension |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Hypoxia-induced pulmonary hypertension |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Males or females aged 18 years and over
2. Resting pulmonary artery pressure ≥25 mmHg
3. Written informed consent must be obtained by the investigator before the subject is screened for the study |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Patients are randomised to:
1. Placebo tds for 3 months
2. Sildenafil 25 mg tds for 3 months, or
3. Sildenafil 100 mg tds for 3 months |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | British Heart Foundation |
| Sponsor name | British Heart Foundation (UK) |
| Sponsor details | 14 Fitzhardinge Street
London
United Kingdom
W1H 6DH |
| Sponsor telephone | +44 (0)20 7935 0185 |
| Sponsor fax | +44 (0)20 7486 5820 |
| Sponsor email | research@bhf.org.uk |
| Sponsor website | http://www.bhf.org.uk/ |
| Contact name | Professor MR Wilkins |
| Contact details | Section on Clinical Pharmacology
Imperial College
Hammersmith Hospital
Du Cane Road
London
United Kingdom
W12 0NN |
| Contact telephone | +44 (0)20 8383 2049 |
| Contact fax | +44 (0)20 8383 2066 |
| Contact email | m.wilkins@ic.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN41186152 |
| Date last extracted from ISRCTN register | 17/04/2008 |
