| Source of record | UK Trials |
| ISRCTN | ISRCTN21931925 |
| Date ISRCTN assigned | 31/10/2001 |
| Local reference number(s) | PG/97051 |
| Public title | Test of the open artery hypothesis |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Cardiovascular disease |
| Study hypothesis | Effect on ventricular modelling of angioplasty and stenting of the occluded infarct related artery (IRA) among patients with their first Q wave anterior myocardial infarction. |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | Patients with Thrombolysis in Myocardial Infarction (TIMI) grade 0 or I. |
| Participants - exclusion criteria | Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded. |
| Patient information material |
|
| Anticipated start date | 01/03/1997 |
| Anticipated end date | 01/06/1999 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Angiography and angioplasty carried out within 28 days of the acute event. Patients to be randomised into intervention or non-intervention groups.
Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
Remaining patients with TIMI grade 0 or I will be randomised to intervention plus optimal medical therapy or optimal medical therapy alone. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Publications | Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12225709 |
| Sources of funding | British Heart Foundation (UK) (ref: PG/97051) |
| Sponsor name | British Heart Foundation (UK) |
| Sponsor details | 14 Fitzhardinge Street
London
United Kingdom
W1H 6DH |
| Sponsor telephone | +44 (0)20 7935 0185 |
| Sponsor fax | +44 (0)20 7486 5820 |
| Sponsor email | research@bhf.org.uk |
| Sponsor website | http://www.bhf.org.uk/ |
| Contact name | Dr MS Marber |
| Contact details | Dept of Cardiology
The Rayne Institute
St Thomas' Hospital
Lambeth Palace Road
London
United Kingdom
SE1 7EH |
| Contact telephone | +44 (0)20 7836 5454 |
| Contact email | mike.marber@kcl.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN21931925 |
| Date last extracted from ISRCTN register | 17/04/2008 |
