| Source of record | UK Trials |
| ISRCTN | ISRCTN55293778 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | EORTC/GITCCG 40983 |
| Public title | Pre and post operative chemotherapy with oxaliplatin, 5-Fluorouracil (5 FU)/Leucovorin (LV) versus surgery alone in resectable liver metastases from colorectal origin |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Colon, rectum |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. All potentially resectable liver metastases without detectable extra-hepatic tumour
2. Primary tumour resected or resectable
3. No previous chemotherapy with oxaliplatin |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated start date | 01/11/2000 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Arm A: Oxaliplatin 85 mg/m2 (day 1) 5-FU: 2000 mg/m2/cycle (days 1 and 2), Leucovorin: 200 mg/m2 (day 1 and 2), every 2 weeks for 6 cycles before surgery and for 6 cycles following surgery.
Arm B: Surgery alone. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN55293778 |
| Date last extracted from ISRCTN register | 17/04/2008 |
