| Source of record | UK Trials |
| ISRCTN | ISRCTN64336220 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | PRECISE |
| Public title | A randomised double-blind placebo-controlled cancer prevention trial with an estimated duration of 5 years and with 52,000 subjects recruited from the general populations of the UK, Denmark, Sweden, Finland and the United States |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Multiple sites |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | All those aged between 60 and 74 years are eligible except those:
1. With a Southwest Oncology Group (SWOG) performance status score of greater then 1 or equivalent
2. With active liver or kidney disease
3. With a prior diagnosis of cancer
4. With a diagnosed Human Immunodeficiency Virus (HIV) infection
5. With diminished mental capacity
6. Taking 50 micrograms/day or more of selenium supplements |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated end date | 29/06/2001 |
| Status of trial | Completed |
| Target number of participants | 52000 |
| Interventions | Four treatment groups:
1. Placebo
2. 100 micrograms Selenium/day
3. 200 micrograms Selenium/day
4. 300 micrograms Selenium/day |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN64336220 |
| Date last extracted from ISRCTN register | 17/04/2008 |
