| Source of record | UK Trials |
| ISRCTN | ISRCTN66284161 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | G37 |
| Public title | A placebo-controlled trial of nimopidine with cyclophosphamide/cisplatin for the treatment of advanced ovarian cancer |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Ovary |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Confirmed diagnosis of invasive epithelial ovarian cancer
2. International Federation of Gynaecology and Obstetrics (FIGO) stages Tc - Tv
3. 18-70 years old
4. Performance Status less than or equal to 2
5. White Blood Cells at least 4 x 10^9/l
6. Platelets at least 120 x 10^9/l
7. Creatinine or Ethylene Diamine Tetraacetic Acid (EDTA) clearance greater than or equal to 60 ml/min
8. Normal Bilirubin
9. Serum glutamic-oxaloacetic transaminase (SGOT)/Serum glutamic pyruvic transaminase (SGPT) less than or equal to twice normal limit
10. No previous chemotherapy or radiotherapy |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated end date | 01/01/1993 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | 1. Arm A: Placebo tablet
2. Arm B: Nimopidine tablet |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN66284161 |
| Date last extracted from ISRCTN register | 17/04/2008 |
