| Source of record | UK Trials |
| ISRCTN | ISRCTN79815499 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | NAG9402 |
| Public title | An investigation of the predictability of carboplatin plasma concentrations in children following dosing on the basis of surface area of renal function |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Brain and nervous system |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Aged under 18 years
2. Receiving carboplatin on at least two occasions
3. Being treated according to listed UKCCSG protocols (NB9001, NB9301, NB8702, GC8901, CNS9204, CNS9102, WAG8702)
4. Tumour site: Neuroblastoma; Extra-cranial germ cell; Brain |
| Participants - exclusion criteria | Not provided at time of registration |
| Patient information material |
|
| Anticipated end date | 28/02/1997 |
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | Patients receiving two courses of carboplatin are randomised to one of two groups:
1. Group A: Surface area based (course I) followed by renal function based (course II) measurement.
2. Group B: Renal function based (course I) followed by surface area based (course II) measurement. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK
United Kingdom Children's Cancer Study Group (UKCCSG) |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| Contact telephone | +44 (0) 20 7670 4723 |
| Contact fax | +44 (0) 20 7670 4818 |
| Contact email | register@ctu.mrc.ac.uk |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN79815499 |
| Date last extracted from ISRCTN register | 17/04/2008 |
