| Source of record | UK Trials |
| ISRCTN | ISRCTN98387311 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | HD1-82 |
| Public title | Radiotherapy for pathological stage Ia and IIa (Upper) Hodgkin's disease |
| Scientific title |
|
| Acronym | N/A |
| Disease/condition/study domain | Lymphoma (Hodgkin's) |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Non randomised trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. Pathological stage Ia and IIa (upper) Hodgkin's disease
2. Aged 15 to 65 years
|
| Participants - exclusion criteria | Patients with mediastinal disease will not in general be eligible for local radiotherapy alone |
| Patient information material |
|
| Status of trial | Completed |
| Target number of participants | Not provided at time of registration |
| Interventions | This is a non randomised study, patients are grouped according to site and stage of disease:
1. Group A: Patients with pathological stage Ia (neck), IIa (neck) and Ia (axilla) are assigned to local field radiotherapy. Patients with neck disease receive 30 Gy midline in sixteen fractions over 3 weeks followed by an additional 5 Gy to the site of palpable disease. Patients with axillary disease receive 35 Gy midline in sixteen fractions over 3 weeks.
2. Group B: Patients with pathological stage Ia (supraclavicular), IIa (all sites except neck) are assigned to mantle radiotherapy. Patients receive a dose of 35 Gy mid line in twenty fractions over 4 weeks followed by an additional 6 Gy to the anterior mediastinum. |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr - - |
| Contact details | UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
London
United Kingdom
NW1 2DA |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN98387311 |
| Date last extracted from ISRCTN register | 17/04/2008 |
