| Source of record | UK Trials |
| ISRCTN | ISRCTN98249374 |
| Date ISRCTN assigned | 01/07/2001 |
| Local reference number(s) | NHL 2000/06 |
| Public title | International protocol for the treatment of childhood anaplastic large cell lymphoma (ALCL) |
| Scientific title |
|
| Acronym | Not Applicable |
| Disease/condition/study domain | Lymphoma (non-Hodgkin's) |
| Study hypothesis | Not provided at time of registration |
| Design/methodology | Randomised controlled trial |
| Research ethics review | Not provided at time of registration |
| Countries of trial | United Kingdom |
| Participants - inclusion criteria | 1. ALCL diagnosed by local pathologist
2. Slides available for national review
3. Aged <22 years
4. No previous treatment
5. Appropriate ethical approval |
| Participants - exclusion criteria | Not applicable |
| Patient information material |
|
| Anticipated start date | 01/04/2000 |
| Anticipated end date | 31/12/2006 |
| Status of trial | Completed |
| Target number of participants | 40 |
| Interventions | Four arms:
Arm one: MTX (1 g/m2) over 24 hours with intrathecal
Arm two: MTX (1 g/m2) over 24 hours with intrathecal and Vinblastine for one year
Arm three: MTX (3 g/m2) over three hours without intrathecal
Arm four: MTX (3 g/m2) over three hours without intrathecal and Vinblastine for one year |
| Primary outcome measure(s) | Not provided at time of registration |
| Secondary outcome measure(s) | Not provided at time of registration |
| Sources of funding | Cancer Research UK
United Kingdom Children's Cancer Study Group (UKCCSG) |
| Sponsor name | Cancer Research UK |
| Sponsor details | PO Box 123
Lincoln's Inn Fields
London
United Kingdom
WC2A 3PX |
| Sponsor telephone | +44 (0)20 7317 5186 |
| Sponsor fax | +44 (0)20 7487 4302 |
| Sponsor email | kate.law@cancer.org.uk |
| Sponsor website | http://www.cancer.org.uk |
| Contact name | Dr Denise Williams |
| Contact details | Cambridge University Hospitals NHS Foundation Trust
Children's Service
Box No 181
Addenbrookes Hospital
Hills Road
Cambridge
United Kingdom
CB2 2QQ |
| Contact telephone | +44 (0) 1223 216 878 |
| Contact email | denise.williams@addenbrookes.nhs |
| More information | For more up-to-date information please go to the ISRCTN link below. |
| Link to record in ISRCTN Register | ISRCTN98249374 |
| Date last extracted from ISRCTN register | 17/04/2008 |
