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ISRCTN
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ISRCTN92341395
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ClinicalTrials.gov identifier
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Public title
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A Trial to Establish the Role of Leukocyte Concentration and Tissue Type of Transfused Blood in Immunomodulation of Patients Undergoing Elective Surgery for Colorectal Cancer
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Scientific title
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Acronym
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N/A
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Serial number at source
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CRBT
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Colorectal cancer
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Participants - inclusion criteria
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1. Patients undergoing elective resection of colorectal carcinoma
2. No transfusion of blood in the 6 months preceding the operation
3. No transfusion of blood prior to the first postoperative sample
4. No concurrent immunosuppressive medication
5. No previous transfusion reaction requiring cessation of transfusion
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/2000
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Anticipated end date
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31/12/2005
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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1. Arm A: Surgery without transfusion
2. Arm B: Surgery with standard blood transfusion
3. Arm C: Surgery with leucodepleted blood transfusion
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Leicester General Hospital (UK)
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Trial website
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Publications
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Contact name
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Dr
-
-
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Address
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UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Tel
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+44 (0) 20 7670 4723
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Fax
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+44 (0) 20 7670 4818
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Email
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register@ctu.mrc.ac.uk
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Sponsor
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Leicester General Hospital (UK)
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Address
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Gwendolen Road
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City/town
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Leicester
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Zip/Postcode
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LE5 4PW
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Country
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United Kingdom
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Email
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Date applied
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19/08/2002
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Last edited
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20/05/2008
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Date ISRCTN assigned
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19/08/2002
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