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ISRCTN
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ISRCTN83218866
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ClinicalTrials.gov identifier
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Public title
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A Randomised Trial Comparing External Beam Radiotherapy Alone With External Beam Radiotherapy Plus Intraluminal Irradiation for Palliation in Lung Cancer
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Scientific title
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Acronym
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N/A
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Serial number at source
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ILT-2
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Lung (non-small cell) cancer
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Participants - inclusion criteria
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1. Biopsy proven non-small cell lung cancer
2. Fit to receive bronchoscopy
3. Fit to receive external beam radiotherapy
4. Any age
5. Shortness of breath, cough, haemoptysis, dysphagia or chest pain resulting from a primary bronchial tumour
6. No previous or concomitant malignancy, except basal cell carcinomas
7. No symptomatic metastases requiring external beam radiotherapy
8. No previous chest irradiation for lung cancer
9. No bilateral lung tumours or tracheal tumours
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/2000
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Anticipated end date
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31/12/2005
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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1. Schedule A: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour.
2. Schedule B: External beam radiotherapy, a maximum subcutaneous dose of 3250 cGy given in eight fractions over 10 days with a margin of 2 cm around the tumour. Followed by intraluminal radiotherapy, a single dose of 1500 cGy to be given on the last day of external beam radiotherapy.
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Cancer organisations (UK)
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Trial website
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Publications
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Contact name
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Dr
-
-
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Address
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UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Tel
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+44 (0) 20 7670 4723
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Fax
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+44 (0) 20 7670 4818
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Email
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register@ctu.mrc.ac.uk
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Sponsor
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UK Co-ordinating Committee for Cancer Research (UKCCCR)
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Address
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MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Date applied
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19/08/2002
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Last edited
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20/05/2008
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Date ISRCTN assigned
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19/08/2002
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