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ISRCTN
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ISRCTN78267267
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ClinicalTrials.gov identifier
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Public title
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Cryotherapy versus Salicylic Acid with Monochloracetic Acid for the Treatment of Verrucae: A Randomised Controlled Trial
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0530132857
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Study hypothesis
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Verrucae, or warts, are a common, infectious and sometimes painful problem, but it is uncertain which is the most effective treatment. We plan to compare two commonly used treatments for warts: salicylic acid with monochloracetic acid or cryotherapy. We are interested to know how effective the two treatments are in cleaning up the warts and also how cost effective the two treatments are compared to one another. Patients will also be asked about acceptability with their treatment and possible side effects such as pain.
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Lay summary
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Skin and Connective Tissue Diseases: Warts
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Participants - inclusion criteria
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Not provided at time of registration
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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29/10/2003
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Anticipated end date
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31/08/2004
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Status of trial
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Stopped |
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Patient information material
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Target number of participants
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133 in each treatment group
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Interventions
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Database analysis, Questionnaires, Randomised Controlled Trial - to compare:
1. Cryotherapy
2. Salicylic acid with monochloracetic acid
For treatment of plantar warts
August 2008: Trial stopped 2006.
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Primary outcome measure(s)
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A recent systematic review has highlighted the uncertainty with respect to the optimal treatment of verrucae and warts (Gibbs Set et al, BMJ, 2002). Freezing warts using cryotherapy is widespread but there is little evidence showing it is effective. However, it may be relatively cost effective compared with chemical treatments in that fewer visits may be required to eradicate the condition. There is a need for a randomised controlled trial with a cost effectiveness analysis to ascertain which is the best approach. The evidence base would aid clinical decision makers and also health care managers in resource allocation
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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North Central London Research Consortium (UK)
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Trial website
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Publications
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Contact name
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Miss
Julie C
Day
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Address
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Podiatry Department
First Floor East Wing
St Pancras Hospital
4 St Pancras Way
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City/town
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London
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Zip/Postcode
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NW1 0PE
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Country
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United Kingdom
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Tel
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+44 (0)20 7530 3871
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Email
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jules.day@virgin.net
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Sponsor
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Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
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Address
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The Department of Health,
Richmond House,
79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.dh.gov.uk/Home/fs/en
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Date applied
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30/09/2004
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Last edited
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27/09/2011
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Date ISRCTN assigned
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30/09/2004
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