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ISRCTN
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ISRCTN77150103
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ClinicalTrials.gov identifier
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Public title
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Clinical medication review by a pharmacist of patients on repeat prescriptions in general practice
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Scientific title
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Acronym
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N/A
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Serial number at source
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HTA 93/22/09
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Study hypothesis
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This randomised controlled clinical trial will examine whether a suitably experienced pharmacist can conduct effective clinical medication review of patients on repeat prescriptions. The study will compare this approach with a control group who will be part of the normal review mechanisms for repeat prescriptions. The pharmacist will be an experienced clinical pharmacist with the appropriate clinical and consultation skills.
The objective is to assess whether clinical medication review by a pharmacist is a cost-effective method for improving the extent and quality of clinical control of repeat prescribing, compared with that achieved by the practices' normal procedures.
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Ethics approval
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Not provided at time of registration.
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Repeat prescriptions
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Participants - inclusion criteria
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Not provided at time of registration.
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Participants - exclusion criteria
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Not provided at time of registration.
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Anticipated start date
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01/03/1999
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Anticipated end date
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31/03/2001
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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1200
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Interventions
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A total of 1200 patients from four practices will be randomised to the active or control group. Patients in the active group will be called for an appointment with the pharmacist at the surgery. The pharmacist will assess the continuing appropriateness of the medication regime and make appropriate recommendations (in conjunction with the GP). The control group will receive standard care.
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Primary outcome measure(s)
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The primary outcome was the number of repeat medication changes per patient over a 12-month period. The secondary outcome was the effect on the medication costs. The intervention group was compared with the control group to see whether a review had taken place, the numbers of medication changes, the numbers of repeat medications and the numbers of dosage times. The effects of the medication review clinics were considered in relation to practice consultations, outpatient consultations, hospital admissions and deaths from any cause. The number and nature of the pharmacist¿s interventions and recommendations were recorded, together with whether the recommendations were accepted by the GP.
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Secondary outcome measure(s)
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Not provided at time of registration.
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Sources of funding
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NIHR Health Technology Assessment Programme - HTA (UK)
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Trial website
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Publications
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2001 results in http://www.ncbi.nlm.nih.gov/pubmed/11739221
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Contact name
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Dr
Arnold
Zermansky
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Address
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School of Healthcare Studies
University of Leeds
Division of Academic Pharmacy Practice
Room 2.23 Baines Wing
PO Box 214
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City/town
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Leeds
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Zip/Postcode
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LS2 9UT
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Country
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United Kingdom
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Tel
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+44 (0)113 3431340
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Fax
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+44 (0)113 3431284
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Email
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zermansky@btinternet.com
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Sponsor
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Department of Health (UK)
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Address
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Quarry House
Quarry Hill
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City/town
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Leeds
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Zip/Postcode
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LS2 7UE
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Country
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United Kingdom
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Email
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Sheila.Greener@doh.gsi.gov.uk
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Sponsor website:
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http://www.dh.gov.uk/en/index.htm
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Date applied
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25/04/2003
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Last edited
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27/08/2009
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Date ISRCTN assigned
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25/04/2003
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