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ISRCTN
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ISRCTN76536440
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ClinicalTrials.gov identifier
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Public title
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Washed blood components in adult acute leukemia
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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Not provided at time of registration
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised active controlled parallel group trial
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Countries of recruitment
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United States of America
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Disease/condition/study domain
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Acute Leukemia
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Participants - inclusion criteria
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Adult patients with acute leukemia undergoing full dose remission induction chemotherapy.
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Participants - exclusion criteria
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Does not match inclusion criteria
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Anticipated start date
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01/01/1991
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Anticipated end date
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31/12/1994
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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43
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Interventions
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The control intervention was leukocyte reduced red cell and platelet transfusions, the standard practice in most hospitals.
The experimental intervention was leukocyte reduced red cell and platelet transfusions that had also been plasma reduced by washing.
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Primary outcome measure(s)
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Added 14/08/09:
1. Platelet transfusion refractoriness
2. Infectious and bleeding complications
3. Overall survival.
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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University of Rochester (USA)
CaridianBCT Inc. (formerly Gambro BCT Inc.) (USA)
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Trial website
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Publications
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2004 results in http://www.ncbi.nlm.nih.gov/pubmed/15588315
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Contact name
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Dr
Neil
Blumberg
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Address
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601 Elmwood Avenue
Box 608
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City/town
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Rochester
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Zip/Postcode
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14642
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Country
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United States of America
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Tel
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+1 585 275 9656
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Fax
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+1 585 273 3002
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Email
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neil_blumberg@urmc.rochester.edu
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Sponsor
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University of Rochester (USA)
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Address
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601 Elmwood Avenue
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City/town
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Rochester
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Zip/Postcode
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14642
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Country
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United States of America
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Email
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neil_blumberg@urmc.rochester.edu
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Date applied
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02/12/2004
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Last edited
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14/08/2009
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Date ISRCTN assigned
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06/12/2004
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