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Oxford Community Treatment Order Evaluation Trial
DOI 10.1186/ISRCTN73110773
ClinicalTrials.gov identifier
EudraCT number
Public title Oxford Community Treatment Order Evaluation Trial
Scientific title A single centre randomised controlled trial of Community Treatment Order versus treatment on leave in patients with psychosis
Acronym OCTET
Serial number at source NIHR: RP-PG-0606-1006
Study hypothesis The overall hypothesis is that the use of Community Treatment Orders (CTOs) in patients with psychosis and a history of compulsory admissions will result in a reduction in readmissions to hospital compared to treatment on leave. To test the hypothesis, the primary outcome measure is psychiatric hospitalisation in the 12-month follow-up period.
Lay summary Not provided at time of registration
Ethics approval North and South Staffordshire Research Ethics Committee awarded full ethical approval on 30th October 2008 (ref: 08/H1204/131)
Study design Single centre randomised controlled trial
Countries of recruitment United Kingdom
Disease/condition/study domain Psychosis
Participants - inclusion criteria 1. Aged 18 - 65 years (reflecting national service configurations), either sex
2. Diagnosed with psychosis
3. Currently admitted under a treatment section (section 3 or 37) of the Mental Health Act
4. Judged by their clinicians (psychiatrist and Approved Mental Health Professional) to need ongoing community treatment under compulsion
5. Able give written and informed consent
6. Not already participating in the study
Participants - exclusion criteria Subject to additional legal restrictions on treatment
Anticipated start date 03/11/2008
Anticipated end date 31/10/2010
Status of trial Completed
Patient information material Can be found at http://www.psychiatry.ox.ac.uk/research/researchunits/socpsych/research/octetinfo/participantinfo
Target number of participants 300
Interventions Eligible patients will be identified from current involuntary inpatients under the care of Community Mental Health Teams (CMHTs) and Assertive Outreach Teams (AOTs) who have agreed to collaborate. Teams must be able, and agree, to offer contact with the patient approximately weekly in either arm.

Access to patients is through a member of the care team. An independent researcher will assess and record the patient's capacity before seeking written informed consent. Participants will be interviewed at baseline and at 6 and 12 months, using appropriate validated and standardised questionnaires. Data related to the primary outcome measure (plus several secondary measures) will be collected from patients' medical records. After 12 months in the trial, care returns to normal.
Primary outcome measure(s) Rate of readmission to hospital in a 12-month follow-up period
Secondary outcome measure(s) Measured at baseline, 6 and 12 months:
1. Number of days in psychiatric hospital
2. Time to readmissions
3. Engagement with clinical services and loss to care
4. Adherence to prescribed medication
5. Satisfaction with services
6. Clinical and social outcomes
Sources of funding National Institute of Health Research (NIHR) (UK) - Programme Grant for Applied Research (PGfAR) (ref: RP-PG-0606-1006)
Trial website
Publications 1. 2013 results in http://www.ncbi.nlm.nih.gov/pubmed/23537605
Contact name Prof  Tom  Burns
  Address University Department of Psychiatry
Warneford Hospital
  City/town Oxford
  Zip/Postcode OX3 7JX
  Country United Kingdom
  Tel +44 (0)1865 226 474
  Email tom.burns@psych.ox.ac.uk
Sponsor Oxfordshire and Buckinghamshire Mental Health NHS Foundation Trust (UK)
  Address Littlemore Mental Health Centre
Sandford Road
  City/town Oxford
  Zip/Postcode OX4 4XN
  Country United Kingdom
  Sponsor website: http://www.obmh.nhs.uk/
Date applied 11/12/2009
Last edited 21/06/2013
Date ISRCTN assigned 20/01/2010
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