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ISRCTN
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ISRCTN71224182
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ClinicalTrials.gov identifier
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Public title
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Randomized Trial of Heat Recovery Ventilators (HRVs) for the Prevention of Severe Lower Respiratory Tract Infection (LRTI) in Inuit Infants in Baffin Region, Nunavut, Canada
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Scientific title
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Acronym
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N/A
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Serial number at source
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PERD-089
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Study hypothesis
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Heat Recovery Ventilators, by improving indoor air ventilation and indoor air quality will reduce the incidence of severe lower respiratory tract infection requiring admission to hospital in Inuit infants in Baffin Region, Nunavut.
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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Canada
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Disease/condition/study domain
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Bronchiolitis, Pneumonia
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Participants - inclusion criteria
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Inuit infants 0-2 years of age living in eligible communities in Baffin Region, Nunavut, Canada
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Participants - exclusion criteria
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Children with underlying congenital malformations known to increase the risk of LRTI, including congenital lung malformations and congenital heart disease will be excluded from the study, as well as children with underlying conditions known to increase the risk of LRTI, including cystic fibrosis, severe developmental delay, and immunodeficiency. Houses where it is technically impossible to install the HRV will be excluded from the study. Only households providing informed consent will be allowed to participate in the trial.
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Anticipated start date
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15/09/2005
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Anticipated end date
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15/09/2008
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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150
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Interventions
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Heat Recovery Ventilator versus placebo Heat Recovery Ventilator
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Primary outcome measure(s)
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Admission to hospital for severe lower respiratory tract infection
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Secondary outcome measure(s)
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Effect of Heat Recovery Ventilators on indoor CO2, Air change rate, respiratory symptoms, occupant comfort, and visits to the nursing station for respiratory illness.
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Sources of funding
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Program of Energy Research and Development (PERD) PERD-089
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Trial website
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Publications
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Contact name
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Dr
Thomas
Kovesi
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Address
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Children's Hospital of Eastern Ontario
401 Smyth Rd
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City/town
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Ottawa
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Zip/Postcode
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K1H 8L1
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Country
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Canada
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Sponsor
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Program of Energy Research and Development (Canada)
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Address
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CANMET Energy Technology Centre - Ottawa
Natural Resources Canada
580 Booth Street
13th floor Haanel Drive
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City/town
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Ottawa
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Zip/Postcode
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K1A 0E4
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Country
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Canada
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Date applied
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15/08/2005
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Last edited
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08/05/2007
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Date ISRCTN assigned
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04/11/2005
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