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ISRCTN
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ISRCTN67680497
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ClinicalTrials.gov identifier
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Public title
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The randomised controlled trial to evaluate effectiveness of gargling for the prevention of upper respiratory tract infections
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Scientific title
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Acronym
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The Great Cold Study 1
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Serial number at source
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N/A
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Study hypothesis
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Gargling, especially with gargle medicine, is effective for the prevention of upper respiratory tract infections (URTIs).
The follow-up period is 60 days.
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised open label controlled trial
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Countries of recruitment
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Japan
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Disease/condition/study domain
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Upper respiratory tract infections
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Participants - inclusion criteria
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Healthy volunteers aged 18-65 years
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/11/2002
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Anticipated end date
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30/04/2003
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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300
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Interventions
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Gargling with tap water, gargling with diluted povidone-iodine, and usual care
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Primary outcome measure(s)
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Incidence of upper respiratory track infections (URTI).
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Secondary outcome measure(s)
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Severity of upper respiratory track infections (URTI).
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Sources of funding
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1. Uehara Memorial Foundation (Japan)
2. Suzuken Memorial Foundation (Japan)
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Trial website
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Publications
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1. 2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16242593
2. 2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17878657
3. 2008 results in http://www.ncbi.nlm.nih.gov/pubmed/19087312
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Contact name
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Prof
Takashi
Kawamura
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Address
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Yoshida-Honmachi
Sakyo-ku
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City/town
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Kyoto
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Zip/Postcode
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606-8501
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Country
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Japan
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Tel
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+81 (0)75 753 2411
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Fax
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+81 (0)75 753 2424
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Email
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kawax@kuhp.kyoto-u.ac.jp
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Sponsor
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Kyoto University (Japan)
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Address
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Yoshida-Honmachi
Sakyo-ku
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City/town
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Kyoto
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Zip/Postcode
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606-8501
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Country
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Japan
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Tel
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+81 (0)75 753 7531
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Fax
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+81 (0)75 753 2091
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Email
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info@mail.adm.kyoto-u.ac.jp
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Date applied
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26/10/2004
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Last edited
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24/08/2009
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Date ISRCTN assigned
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03/11/2004
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