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ISRCTN
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ISRCTN67128938
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DOI
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10.1186/ISRCTN67128938
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ClinicalTrials.gov identifier
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EudraCT number
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Public title
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UK Alcohol Treatment Trial
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Scientific title
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Acronym
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UKATT
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Serial number at source
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G9700729
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Study hypothesis
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1. To conduct a multi-centre trial of treatment for alcohol problems within the context of the UK treatment system
2. To examine outcomes from a socially based treatment which both theory and research suggest may be effective and cost-effective compared with MET
3. To enquire what types of patient are suited to MET and what types of patient do not benefit from MET and may therefore need a more intensive form of treatment.
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Neuroscience, psychiatry
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Participants - inclusion criteria
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A Diagnostic and Statistical Manual of Mental Disorders - Fourth Edition (DSM-IV) diagnosis of alcohol abuse or alcohol dependence
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Participants - exclusion criteria
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1. Less than 16 years old
2. Abstinence from drinking during 3 months prior to screening
3. Currently receiving another form of alcohol treatment;
4. Intending to seek another form of alcohol treatment within 3 months
5. Other drug use the main problem area
6. Recommended by their clinician for treatment for their other drug use
7. Unable to provide a trace contact
8. Has an uncontrolled mental illness preventing treatment compliance
9. Has a severe language or cognitive problem
10. Has previously been entered into UKATT
11. Is a significant other or network member of an existing UKATT client;
12. Will definitely be moving to another area within 15 months
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Anticipated start date
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01/04/1998
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Anticipated end date
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31/10/2002
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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720
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Interventions
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Motivational Enhancement Therapy (MET)
Social Behaviour Network Therapy (SBNT)
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Primary outcome measure(s)
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Categorical outcome of treatment plus continuous change in levels of:
1. Alcohol consumption
2. Gamma-glutamyl transferase (GGT)
3. Alcohol dependence
4. Alcohol-related problems
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Medical Research Council (UK)
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Trial website
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Publications
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1. 2001 protocol in http://www.ncbi.nlm.nih.gov/pubmed/11139410
2. 2005 results in http://www.ncbi.nlm.nih.gov/pubmed/16150764
3. 2006 results in http://www.ncbi.nlm.nih.gov/pubmed/16393192
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Contact name
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Dr
J
Orford
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Address
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School of Psychology
University of Birmingham
Edgbaston
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City/town
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Birmingham
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Zip/Postcode
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B15 2TT
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Country
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United Kingdom
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Tel
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+44 (0)121 414 4918
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Email
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j.f.orford@bham.ac.uk
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Sponsor
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Medical Research Council (MRC) (UK)
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Address
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20 Park Crescent
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City/town
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London
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Zip/Postcode
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W1B 1AL
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Country
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United Kingdom
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Tel
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+44 (0)20 7636 5422
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Fax
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+44 (0)20 7436 6179
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Email
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clinical.trial@headoffice.mrc.ac.uk
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Sponsor website:
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http://www.mrc.ac.uk
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Date applied
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23/10/2000
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Last edited
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24/11/2010
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Date ISRCTN assigned
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23/10/2000
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