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ISRCTN
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ISRCTN66959365
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ClinicalTrials.gov identifier
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Public title
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Perioperative renal protection in patients subject to cardio-pulmonary bypass
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0123138282
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Study hypothesis
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To examine potential methods of protecting the kidney during and immediately after heart surgery using cardiopulmonary bypass.
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Cardiopulmonary bypass
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Participants - inclusion criteria
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1. Aged greater than 70 years
2. Pre-existing renal disease
3. Not on renal replacement therapy
4. Pre-operative serum creatinine greater than 130 umol/l
5. Type one diabetes mellitus
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Participants - exclusion criteria
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Only first time coronary artery surgery will be included
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Anticipated start date
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01/01/2003
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Anticipated end date
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01/04/2003
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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60 patients, 20 controls
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Interventions
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To examine potential methods of protecting the kidney during and immediately after heart surgery using cardiopulmonary bypass.
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Primary outcome measure(s)
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Determine whether perioperative low dose frusemide, dopamine or aminophylline would improve clinical and biochemical outcomes in adult patients, at increased risk of kidney dysfunction.
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Secondary outcome measure(s)
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No secondary outcome measures
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Sources of funding
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1. University Hospitals of Leicester NHS Trust (UK)
2. Departmental funding (UK)
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Trial website
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Publications
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Contact name
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Mr
T
Spyt
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Address
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University Hospitals of Leicester
c/o Research and Development Office
Leicester General Hospital NHS Trust
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City/town
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Leicester
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Zip/Postcode
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LE1 4PW
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Country
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United Kingdom
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Tel
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+44 (0)116 258 4109
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Fax
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+44 (0)116 258 4226
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Email
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Sponsor
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Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
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Address
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The Department of Health
Richmond House
79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Fax
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+44 (0)20 7307 2623
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.dh.gov.uk/Home/fs/en
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Date applied
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30/09/2005
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Last edited
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26/04/2011
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Date ISRCTN assigned
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30/09/2005
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