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ISRCTN
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ISRCTN66284870
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ClinicalTrials.gov identifier
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Public title
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Randomised controlled trial of Skin Prick Testing
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Scientific title
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Acronym
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SPT
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Serial number at source
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06/039/SMI
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Study hypothesis
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Does allergy assessment and appropriate advice in general practice enhance the care of patients with asthma and rhinitis and is it cost effective compared with routine medical care?
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Lay summary
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Not provided at time of registration
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Ethics approval
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Ethics approval received from the Multicentre Research Ethics Committee on the 26th May 2003 (ref: MREC/02/10/13).
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Asthma and rhinitis
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Participants - inclusion criteria
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Patients with a working diagnosis of asthma and/or rhinoconjunctivitis
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Participants - exclusion criteria
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1. Less than 5 years or greater than 50 years
2. Terminal illness
3. Confusional state
4. History of anaphylaxis
5. Tested in the preceding two years
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Anticipated start date
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01/05/2006
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Anticipated end date
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01/05/2008
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Status of trial
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Completed |
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Patient information material
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Not available in web format, please use the contact details below to request a patient information sheet
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Target number of participants
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528 patients
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Interventions
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Allergy intervention - structured allergy history and skin prick testing and appropriate advice on allergy avoidance versus routine medical care
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Primary outcome measure(s)
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1. Symptom scores (validated scale for asthma and rhinoconjunctivitis)
2. Health-related quality of life (using child or adult specific instruments)
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Secondary outcome measure(s)
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1. Patients' subjective assessment of symptomatic improvement
2. Change in patient management (introduction or withdrawal of allergen avoidance)
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Sources of funding
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1. Brighton and Sussex Medical School (UK) - originally held by from Southampton University
2. Alk-Abello Ltd (UK) (ref: D105 R107)
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Trial website
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Publications
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1. 2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19135237
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Contact name
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Prof
Helen
Smith
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Address
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Brighton and Sussex Medical School
Mayfield House
University of Brighton
Falmer
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City/town
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Brighton
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Zip/Postcode
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BN1 9PH
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Country
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United Kingdom
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Tel
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+44 (0)1273 644563
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Email
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h.e.smith@bsms.ac.uk
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Sponsor
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Brighton and Sussex University Hospitals NHS Trust (UK)
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Address
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Royal Sussex County Hospital
Eastern Road
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City/town
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Brighton
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Zip/Postcode
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BN2 5BE
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Country
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United Kingdom
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Tel
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+44 (0)1273 696955
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Email
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scott.harfield@bsuh.nhs.uk
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Sponsor website:
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http://www.bsuh.nhs.uk/
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Date applied
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25/04/2006
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Last edited
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08/02/2012
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Date ISRCTN assigned
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06/06/2006
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