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ISRCTN
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ISRCTN61138858
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DOI
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10.1186/ISRCTN61138858
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ClinicalTrials.gov identifier
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EudraCT number
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Public title
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The effectiveness of non-surgical orthodontic treatment for the treatment of severe class II growth anomalies
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Scientific title
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Acronym
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N/A
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Serial number at source
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G9410454
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Study hypothesis
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To evaluate the effectiveness of different methods of orthodontic growth modification for the treatment of mandibular deficiency. The methods that are being compared are: (1) Early treatment with a Twin Block appliance and no treatment (2) Later treatment with a Herbst appliance or a Twin Block.
This trial was continued by ISRCTN26364810 - grant G9901331.
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Lay summary
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Dental
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Participants - inclusion criteria
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Children with an overjet of greater than 7 mm
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Participants - exclusion criteria
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Craniofacial syndrome
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Anticipated start date
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01/04/1997
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Anticipated end date
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01/04/2001
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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480
Added 20/08/09: 2 years follow-up
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Interventions
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Early treatment with a Twin Block appliance and no treatment.
Later treatment with a Herbst appliance or a Twin Block.
This trial was continued by ISRCTN26364810 - grant G9901331.
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Primary outcome measure(s)
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Dental and skeletal change, self esteem and patient preference
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Medical Research Council (MRC) (UK)
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Trial website
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Publications
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Contact name
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Professor
Kevin
O'Brien
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Address
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Department of Dental Medicine and Surgery
University Dental Hospital of Manchester
Higher Cambridge Street
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City/town
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Manchester
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Zip/Postcode
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M15 6FH
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Country
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United Kingdom
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Email
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Sponsor
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Medical Research Council (MRC) (UK)
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Address
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20 Park Crescent
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City/town
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London
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Zip/Postcode
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W1B 1AL
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Country
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United Kingdom
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Tel
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+44 (0)20 7636 5422
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Fax
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+44 (0)20 7436 6179
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Email
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clinical.trial@headoffice.mrc.ac.uk
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Sponsor website:
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http://www.mrc.ac.uk
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Date applied
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17/10/2000
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Last edited
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17/07/2012
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Date ISRCTN assigned
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17/10/2000
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