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ISRCTN
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ISRCTN60986572
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ClinicalTrials.gov identifier
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Public title
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The Hertfordshire Physical Activity Trial
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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The aim of the study is to determine whether differential responses to a physical activity training programme are seen between individuals with low birth weight compared to individuals with a normal birth weight.
More details can be found at: http://www.mrc.ac.uk/ResearchPortfolio/Grant/Record.htm?RecType=Unit&AgreementId=88572&CaseId=21340
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Lay summary
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Ethics approval
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Ethics approval received from the Hertfordshire Local Research Ethics Committee on the 23rd May 2005 (ref: 05/Q0201/23).
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Study design
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Randomised controlled single-centre trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Metabolic risk
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Participants - inclusion criteria
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1. Healthy volunteers from the Hertfordshire Birth Cohort
2. Male and female, born between 1931 - 1939
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Participants - exclusion criteria
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1. Diabetes
2. Untreated hypertension
3. Ischaemic heart disease
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Anticipated start date
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17/01/2007
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Anticipated end date
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01/03/2008
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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100
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Interventions
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Aerobic exercise programme versus care as usual. The control group continue with their normal activities. The exercise group take part in a fully supervised 12- week aerobic exercise programme. There are three sessions each week and each one lasts sixty minutes.
Contact for queries:
Miss Jessica Horton
Email: Jessica.Horton@mrc-epid.cam.ac.uk
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Primary outcome measure(s)
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Clustered Metabolic Risk Score.
Study participants return for their second visit thirteen weeks after their baseline visit. The outcomes will be measured at this time.
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Secondary outcome measure(s)
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1. Body composition
2. Insulin sensitivity
3. Physical fitness
Study participants return for their second visit thirteen weeks after their baseline visit. The outcomes will be measured at this time.
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Sources of funding
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Medical Research Council Epidemiology Unit (UK)
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Trial website
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Publications
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1. 2009 protocol in http://www.ncbi.nlm.nih.gov/pubmed/19545359
2. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20052455
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Contact name
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Prof
Nick
Wareham
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Address
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Medical Research Council Epidemiology Unit
Institute of Metabolic Science
BOX 285
Hills Road
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City/town
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Cambridge
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Zip/Postcode
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CB2 0QQ
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Country
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United Kingdom
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Sponsor
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Medical Research Council Epidemiology Unit (UK)
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Address
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Institute of Metabolic Science
BOX 285
Addenbrooke's Hospital
Hills Road
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City/town
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Cambridge
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Zip/Postcode
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CB2 0QQ
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Country
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United Kingdom
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Sponsor website:
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http://www.mrc-epid.cam.ac.uk/
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Date applied
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31/10/2007
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Last edited
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27/04/2010
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Date ISRCTN assigned
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23/01/2008
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