Welcome
Support Centre
30 September 2014 
ISRCTN Register - International Standard Randomized Controlled Trial Number
Trial registration
Unique identification scheme
International databases
home  |   my details  |   ISRCTN Register  |   mRCT  |   links  |   information  |   news
Find trials
ISRCTN Register
tips on searching

Registration
New application
Updating record

Information
introduction
governing board
ISRCTN FAQs
data set
letter of agreement
request information
guidance notes
statistics

[ Print-friendly version ]
The Hertfordshire Physical Activity Trial
ISRCTN ISRCTN60986572
DOI 10.1186/ISRCTN60986572
ClinicalTrials.gov identifier
EudraCT number
Public title The Hertfordshire Physical Activity Trial
Scientific title
Acronym N/A
Serial number at source N/A
Study hypothesis The aim of the study is to determine whether differential responses to a physical activity training programme are seen between individuals with low birth weight compared to individuals with a normal birth weight.

More details can be found at: http://www.mrc.ac.uk/ResearchPortfolio/Grant/Record.htm?RecType=Unit&AgreementId=88572&CaseId=21340
Lay summary
Ethics approval Ethics approval received from the Hertfordshire Local Research Ethics Committee on the 23rd May 2005 (ref: 05/Q0201/23).
Study design Randomised controlled single-centre trial
Countries of recruitment United Kingdom
Disease/condition/study domain Metabolic risk
Participants - inclusion criteria 1. Healthy volunteers from the Hertfordshire Birth Cohort
2. Male and female, born between 1931 - 1939
Participants - exclusion criteria 1. Diabetes
2. Untreated hypertension
3. Ischaemic heart disease
Anticipated start date 17/01/2007
Anticipated end date 01/03/2008
Status of trial Completed
Patient information material
Target number of participants 100
Interventions Aerobic exercise programme versus care as usual. The control group continue with their normal activities. The exercise group take part in a fully supervised 12- week aerobic exercise programme. There are three sessions each week and each one lasts sixty minutes.

Contact for queries:
Miss Jessica Horton
Email: Jessica.Horton@mrc-epid.cam.ac.uk
Primary outcome measure(s) Clustered Metabolic Risk Score.

Study participants return for their second visit thirteen weeks after their baseline visit. The outcomes will be measured at this time.
Secondary outcome measure(s) 1. Body composition
2. Insulin sensitivity
3. Physical fitness

Study participants return for their second visit thirteen weeks after their baseline visit. The outcomes will be measured at this time.
Sources of funding Medical Research Council Epidemiology Unit (UK)
Trial website
Publications 1. 2009 protocol in http://www.ncbi.nlm.nih.gov/pubmed/19545359
2. 2010 results in http://www.ncbi.nlm.nih.gov/pubmed/20052455
Contact name Prof  Nick  Wareham
  Address Medical Research Council Epidemiology Unit
Institute of Metabolic Science
BOX 285
Hills Road
  City/town Cambridge
  Zip/Postcode CB2 0QQ
  Country United Kingdom
Sponsor Medical Research Council Epidemiology Unit (UK)
  Address Institute of Metabolic Science
BOX 285
Addenbrooke's Hospital
Hills Road
  City/town Cambridge
  Zip/Postcode CB2 0QQ
  Country United Kingdom
  Sponsor website: http://www.mrc-epid.cam.ac.uk/
Date applied 31/10/2007
Last edited 27/04/2010
Date ISRCTN assigned 23/01/2008
Submit your trial protocol
Submit to Trials journal
Follow us on Twitter
© 2014 ISRCTN unless otherwise stated.