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ISRCTN
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ISRCTN58762744
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ClinicalTrials.gov identifier
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Public title
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A randomised controlled trial of the use of topical application of tranexamic acid in primary cemented total hip replacement
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0155164510
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Study hypothesis
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Can we reduce blood loss associated with total hip replacement by using topical tranexamic acid?
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Lay summary
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Not provided at time of registration
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Ethics approval
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Added 14 October 2008: North West MREC Greater Manchester Strategic Health Authority, ref 05/MRE08/10, favourable ethical opinion on 11/04/2005, extended 02/02/2006
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Musculoskeletal Diseases: Total hip replacement
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Participants - inclusion criteria
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Patients having unilateral primary cemented total hip replacement.
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Participants - exclusion criteria
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1. Allergic to tranexamic acid
2. Pregnancy
3. History of DVT/pulmonary embolus
4. Patients involved in other trials
5. Known bleeding problems
6. Concurrent treatment with warfarin
7. Low dose molecular weight heparin or conventional heparin
8. Paget's disease or revision total hip replacement
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Anticipated start date
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01/06/2005
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Anticipated end date
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31/12/2006
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Status of trial
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Completed |
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Patient information material
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Not available in web format, please use the contact details below to request a patient information sheet
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Target number of participants
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124
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Interventions
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Randomised controlled trial
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Primary outcome measure(s)
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Reduction in blood loss
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Pennine Acute Hospitals NHS Trust (UK), NHS R&D Support Funding
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Trial website
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Publications
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Contact name
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Mr
Sattar
Alshryda
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Address
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Dept of Orthopaedics
Fairfield General Hospital
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City/town
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Bury
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Zip/Postcode
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BL9 7TD
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Country
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United Kingdom
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Tel
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+44 077950 78485
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Fax
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+44
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Email
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Sattar26@hotmail.com
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Sponsor
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Record Provided by the NHSTCT Register - 2006 Update - Department of Health
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Address
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The Department of Health, Richmond House, 79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.dh.gov.uk/Home/fs/en
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Date applied
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29/09/2006
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Last edited
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28/09/2011
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Date ISRCTN assigned
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29/09/2006
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