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ISRCTN
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ISRCTN57835722
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ClinicalTrials.gov identifier
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Public title
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The effect of pharmacological agents on uterine junctional zone contractions during mock embryo transfer: a randomised double blind study
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0084096582
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Study hypothesis
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To assess if junctional zone contractions can be reduced by pharmacological agents.
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Lay summary
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised double blind study
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Pregnancy and Childbirth: Embryo transfer
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Participants - inclusion criteria
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Not provided at time of registration
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/04/2000
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Anticipated end date
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10/12/2003
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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80
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Interventions
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The patient's baseline junctional zone contractions will be established following a 5 minute scan. Video tapes taken of both the pre and post mock embryo transfer will be assessed by two researchers who will be unaware of treatment.
20 patients allocated to the nitric oxide group, 20 to the non-steroidal anti-inflammatory group, 20 control and 20 to the COX-2 inhibitor group.
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Primary outcome measure(s)
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1. Number of contractions per unit time
2. Speed of contractions in cm/min
3. Type of contractions
4. Speed of Echovist
5. Distance traveled by Echovist
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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The North and South Bank Research and Development Consortium (UK)
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Trial website
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Publications
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Contact name
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Dr
Frank
Biervliet
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Address
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Academic Department of Obstetrics & Gynaecology
Hull & East Yorkshire (NHS) Trust
The Princess Royal Hospital
Salthouse Road
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City/town
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Hull
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Zip/Postcode
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HU8 9HE
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Country
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United Kingdom
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Tel
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+44 (0)1482 701151
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Email
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Sponsor
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Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
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Address
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The Department of Health,
Richmond House,
79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.dh.gov.uk/Home/fs/en
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Date applied
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30/09/2004
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Last edited
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02/11/2011
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Date ISRCTN assigned
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30/09/2004
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