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ISRCTN
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ISRCTN48076318
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ClinicalTrials.gov identifier
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Public title
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A randomised controlled trial to evaluate the effectiveness of a pharmacist's telephone reminders in reducing mortality in patients receiving polypharmacy
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Scientific title
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Acronym
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N/A
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Serial number at source
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HSRC/HCPF226103
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Study hypothesis
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To investigate the effects of compliance and periodic telephone counselling by a pharmacist on mortality in patients receiving polypharmacy.
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Ethics approval
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Added as of 22/10/2007:
Ethics approval received from the Chinese University of Hong Kong clinical research ethics committee.
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Study design
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Randomised controlled trial
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Countries of recruitment
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Hong Kong
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Disease/condition/study domain
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Compliance to polypharmacy
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Participants - inclusion criteria
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Patients receiving polypharmacy defined as five or more chronic medications who were found to be non-compliant upon first assessment by pharmacist
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Participants - exclusion criteria
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1. Speak non-Cantonese dialects or a different language
2. Conditions that prevented effective communication (for example, patients who are deaf, mute, or have dementia or other psychological disorders)
3. Live in nursing homes with supervised treatment
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Anticipated start date
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01/10/1998
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Anticipated end date
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01/06/1999
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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Added as of 22/10/2007: 502 recruited
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Interventions
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Patients randomised to the intervention group received a 10 - 15 minute telephone call from the pharmacist for education and counselling between clinic visits for 2 years. Patients in the control group did not receive any telephone reminders.
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Primary outcome measure(s)
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Time from randomisation to death from any cause.
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Secondary outcome measure(s)
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1. Changes in the rate of admission to hospital
2. Number of emergency room visits
3. Hospital stay in the two years before and after the screening visit
4. Changes in compliance
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Sources of funding
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Hong Kong SAR Government Health Services Research Committee (Hong Kong)
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Trial website
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Publications
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Results in http://www.ncbi.nlm.nih.gov/pubmed/16916809
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Contact name
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Prof
Juliana CN
Chan
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Address
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Dept of Medicine and Therapeutics
Chinese University of Hong Kong
The Prince of Wales Hospital
Shatin
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City/town
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-
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Zip/Postcode
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-
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Country
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Hong Kong
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Tel
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+852 (0)2632 3138
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Fax
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+852 (0)2632 3108
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Email
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jchan@cuhk.edu.hk
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Sponsor
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Hong Kong Health Services Research Fund (Hong Kong)
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Address
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Health Welfare and Food Bureau
Government Secretariat, HKSAR
20th floor Murray Building
Garden Road
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City/town
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-
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Zip/Postcode
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-
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Country
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Hong Kong
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Tel
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+852 (0)2973 8288
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Fax
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+852 (0)2869 4376
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Email
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hsrf@hwfb.gov.hk
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Sponsor website:
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http://www.fhb.gov.hk/index.html
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Date applied
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05/10/2004
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Last edited
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18/02/2008
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Date ISRCTN assigned
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15/02/2005
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