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ISRCTN
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ISRCTN45115288
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ClinicalTrials.gov identifier
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Public title
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British stomach cancer group trial IV: A randomised trial of cimetidine treatment in gastric cancer
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Scientific title
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Acronym
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N/A
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Serial number at source
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GA3004
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Oesophagus, stomach cancer
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Participants - inclusion criteria
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1. Biopsy proven adenocarcinoma of the stomach, any stage of disease, whether removed curatively or palliatively, or unresectable
2. Able to swallow tablets
3. No other concurrent cancer at other primary sites
4. No other serious illness, limiting prognosis severely
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/1994
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Anticipated end date
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31/03/1995
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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Patients are randomised to one of four treatment arms:
1. Arm A: Cimetidine 400 mg twice daily until death.
2. Arm B: Cimetidine 400 mg once daily until death.
3. Arm C: Placebo tablet twice daily until death.
4. Arm D: Placebo tablet once daily until death.
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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1. Cancer Research UK
2. Smithkline Beecham Pharmaceuticals
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Trial website
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Publications
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Contact name
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Dr
-
-
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Address
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UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Tel
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+44 (0) 20 7670 4723
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Fax
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+44 (0) 20 7670 4818
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Email
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register@ctu.mrc.ac.uk
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Sponsor
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Cancer Research UK (CRUK) (UK)
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Address
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PO Box 123
Lincoln's Inn Fields
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City/town
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London
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Zip/Postcode
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WC2A 3PX
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Country
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United Kingdom
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Tel
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+44 (0)20 7317 5186
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Fax
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+44 (0)20 7487 4302
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Email
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kate.law@cancer.org.uk
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Sponsor website:
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http://www.cancer.org.uk
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Date applied
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01/07/2001
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Last edited
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22/05/2008
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Date ISRCTN assigned
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01/07/2001
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