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ISRCTN
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ISRCTN44967321
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ClinicalTrials.gov identifier
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Public title
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A Study to Compare the Effect of Two Blinded Doses of Casodex (ICI 176,334 100 mg and 150 mg daily) and Castration in the Treatment of Advanced Carcinoma of the Prostate
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Scientific title
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Acronym
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N/A
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Serial number at source
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CASODEX 0307
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Prostate
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Participants - inclusion criteria
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1. Locally advanced stage T3 or T4 carcinoma of the prostate with prostate-specific antigen times five the upper limit of normal or metastatic disease
2. Gleason grade 2-10
3. Evaluable disease
4. Fit to receive treatment
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/1990
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Anticipated end date
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30/06/1993
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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STAGE I PATIENTS: Patients are randomised to either:
1. Casodex 100 mg
2. Casodex 150 mg
3. Castration
STAGE II PATIENTS: Patients are randomised to either:
1. Casodex 150 mg
2. Castration
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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AstraZeneca Pharmaceuticals (UK)
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Trial website
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Publications
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Contact name
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Dr
-
-
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Address
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UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Tel
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+44 (0) 20 7670 4723
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Fax
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+44 (0) 20 7670 4818
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Email
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register@ctu.mrc.ac.uk
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Sponsor
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AstraZeneca Clinical Research Group (UK)
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Address
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10 Logie Mill
Beaverbank Office Park
Lovie Green Road
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City/town
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Edinburgh
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Zip/Postcode
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EH7 4HG
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Country
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United Kingdom
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Sponsor website:
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http://www.astrazeneca.co.uk
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Date applied
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19/08/2002
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Last edited
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22/05/2008
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Date ISRCTN assigned
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19/08/2002
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