Dr Paula Goering
33 Russell Street
+1 (0)416 979 6844
Multi-site pragmatic randomised controlled field trial of Housing First versus treatment as usual in mental health and homelessness
What is the effectiveness, cost/benefit, and cost/effectiveness of Housing First in comparison to care as usual for homeless adults?
Pending as of 08/06/2009 from the Centre for Addiction and Mental Health Research Ethics Board (CAMH REB); expected in Autumn 2009 after each of five primary data collection sites have obtained ethics approval.
Multi-method multi-site unblinded randomised controlled field trial
Primary study design
Secondary study design
Randomised controlled trial
Patient information sheet
Not available in web format, please use the contact details below to request a patient information sheet
Homelessness and serious mental illness
Treatment: provision of rent supplements and case management or assertive community treatment for the duration of the study
Comparison: care as usual
Duration of intervention: Data collection will be ongoing from Sept 2009 to Feb 2013 with duration of intervention from 24 to 42 months.
Duration of follow-up: two years
Primary outcome measures
Housing Stability: Tsemberis Residential Timeline Follow-back Inventory, measured at 6, 12, 18 and 24 months.
Secondary outcome measures
Quality of Life: EQ-5D, measured at 6, 12, 18 and 24 months.
Overall trial start date
Overall trial end date
Participant inclusion criteria
1. Legal adult status
2. Absolute homelessness or precariously housed
3. Presence of a serious mental disorder
4. Aged 18 years and older, either sex
Target number of participants
Participant exclusion criteria
Does not meet inclusion criteria
Recruitment start date
Recruitment end date
Countries of recruitment
Trial participating centre
Centre for Addiction and Mental Health
Health Canada (Canada)
Funding Body Type
Funding Body Subtype
Results and Publications
Publication and dissemination plan
Not provided at time of registration
Intention to publish date
Participant level data
Not provided at time of registration
Results - basic reporting
2011 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/22102645
2012 results in: http://www.ncbi.nlm.nih.gov/pubmed/23031406
2012 childhood learning disability results in: http://www.ncbi.nlm.nih.gov/pubmed/23175737
2014 cumulative childhood adversity results in: http://www.ncbi.nlm.nih.gov/pubmed/24726046
2014 discrimination results in: http://www.ncbi.nlm.nih.gov/pubmed/25196184
2014 results in: http://www.ncbi.nlm.nih.gov/pubmed/24725374
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25734732
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25465295
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25496296
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/25886157
2015 results in: http://www.ncbi.nlm.nih.gov/pubmed/26176621
Stergiopoulos V, O'Campo P, Gozdzik A, Jeyaratnam J, Corneau S, Sarang A, Hwang SW, Moving from rhetoric to reality: adapting Housing First for homeless individuals with mental illness from ethno-racial groups., BMC Health Serv Res, 2012, 12, 345, doi: 10.1186/1472-6963-12-345.
Childhood learning disability results
Patterson ML, Moniruzzaman A, Frankish CJ, Somers JM, Missed opportunities: childhood learning disabilities as early indicators of risk among homeless adults with mental illness in Vancouver, British Columbia., BMJ Open, 2012, 2, 6, doi: 10.1136/bmjopen-2012-001586.
Cumulative childhood adversity results
Patterson ML, Moniruzzaman A, Somers JM, Setting the stage for chronic health problems: cumulative childhood adversity among homeless adults with mental illness in Vancouver, British Columbia., BMC Public Health, 2014, 14, 350, doi: 10.1186/1471-2458-14-350.
Skosireva A, O Campo P, Zerger S, Chambers C, Gapka S, Stergiopoulos V, Different faces of discrimination: perceived discrimination among homeless adults with mental illness in healthcare settings., BMC Health Serv Res, 2014, 14, 1, 376, doi: 10.1186/1472-6963-14-376.
Stergiopoulos V, Gozdzik A, O'Campo P, Holtby AR, Jeyaratnam J, Tsemberis S, Housing First: exploring participants' early support needs, BMC Health Serv Res, 2014 , 14, 167, doi: 10.1186/1472-6963-14-167.
Stergiopoulos V, Hwang SW, Gozdzik A, Nisenbaum R, Latimer E, Rabouin D, Adair CE, Bourque J, Connelly J, Frankish J, Katz LY, Mason K, Misir V, O'Brien K, Sareen J, Schütz CG, Singer A, Streiner DL, Vasiliadis HM, Goering PN; for the At Home/Chez Soi Investigators, Effect of Scattered-Site Housing Using Rent Supplements and Intensive Case Management on Housing Stability Among Homeless Adults With Mental Illness: A Randomized Trial, JAMA, 2015, 313, 9, 905-915, doi: 10.1001/jama.2015.1163.
Goering PN, Streiner DL, Adair C, Aubry T, Barker J, Distasio J, Hwang SW, Komaroff J, Latimer E, Somers J, Zabkiewicz DM, The At Home/Chez Soi trial protocol: a pragmatic, multi-site, randomised controlled trial of a Housing First intervention for homeless individuals with mental illness in five Canadian cities, BMJ Open, 2011, 1, 2, e000323, doi: 10.1136/bmjopen-2011-000323.
Kirst M, Zerger S, Misir V, Hwang S, Stergiopoulos V, The impact of a Housing First randomized controlled trial on substance use problems among homeless individuals with mental illness, Drug Alcohol Depend, 2015 , 146, 24-29, doi: 10.1016/j.drugalcdep.2014.
Zerger S, Bacon S, Corneau S, Skosireva A, McKenzie K, Gapka S, O'Campo P, Sarang A, Stergiopoulos V, Differential experiences of discrimination among ethnoracially diverse persons experiencing mental illness and homelessness, BMC Psychiatry, 2014 , 14, 1, 353, doi: 10.1186/s12888-014-0353-1.
Gozdzik A, Salehi R, O'Campo P, Stergiopoulos V, Hwang SW, Cardiovascular risk factors and 30-year cardiovascular risk in homeless adults with mental illness, BMC Public Health, 2015 , 15, 165, doi: 10.1186/s12889-015-1472-4.
Stergiopoulos V, Gozdzik A, Misir V, Skosireva A, Connelly J, Sarang A, Whisler A, Hwang SW, O'Campo P, McKenzie K, Effectiveness of Housing First with Intensive Case Management in an Ethnically Diverse Sample of Homeless Adults with Mental Illness: A Randomized Controlled Trial, PLoS One, 2015 , 10, 7, e0130281, doi: 10.1371/journal.pone.0130281.