|
ISRCTN
|
ISRCTN37381646
|
|
DOI
|
10.1186/ISRCTN37381646
|
|
ClinicalTrials.gov identifier
|
|
|
EudraCT number
|
|
|
Public title
|
Multicentre aneurysm screening study
|
|
Scientific title
|
|
|
Acronym
|
MASS
|
|
Serial number at source
|
G9533930
|
|
Study hypothesis
|
To assess the effect of ultrasound screening for abdominal aortic aneurysm (AAA) on mortality from ruptured AAA.
|
|
Lay summary
|
Not provided at time of registration
|
|
Ethics approval
|
Not provided at time of registration
|
|
Study design
|
Randomised controlled trial
|
|
Countries of recruitment
|
United Kingdom
|
|
Disease/condition/study domain
|
Cardiovascular
|
|
Participants - inclusion criteria
|
Men aged 65-74 years on GP lists
|
|
Participants - exclusion criteria
|
1. Died before randomisation
2. Incorrect patient demographics
|
|
Anticipated start date
|
17/02/1997
|
|
Anticipated end date
|
16/02/2007
|
|
Status of trial
|
Completed |
|
Patient information material
|
|
|
Target number of participants
|
66,000
|
|
Interventions
|
Ultrasound screening/control
|
|
Primary outcome measure(s)
|
1. Mortality for ruptured AAA as detected through the ONS and overall mortality
2. Cost effectiveness of screening for AAA and its effect on quality of life
|
|
Secondary outcome measure(s)
|
Not provided at time of registration
|
|
Sources of funding
|
Medical Research Council (MRC) (UK)
|
|
Trial website
|
|
|
Publications
|
1. 2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17502630
2. 2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19553269
3. 2012 results in http://www.ncbi.nlm.nih.gov/pubmed/23034729
|
|
Contact name
|
Mr
RAP
Scott
|
|
Address
|
Scott Research Unit
CMEC
St Richard's Hospital
Spitalfield Lane
|
|
City/town
|
Chichester
|
|
Zip/Postcode
|
PO19 4SE
|
|
Country
|
United Kingdom
|
|
Sponsor
|
Medical Research Council (MRC) (UK)
|
|
Address
|
20 Park Crescent
|
|
City/town
|
London
|
|
Zip/Postcode
|
W1B 1AL
|
|
Country
|
United Kingdom
|
|
Tel
|
+44 (0)20 7636 5422
|
|
Fax
|
+44 (0)20 7436 6179
|
|
Email
|
clinical.trial@headoffice.mrc.ac.uk
|
|
Sponsor website:
|
http://www.mrc.ac.uk
|
|
Date applied
|
06/04/2000
|
|
Last edited
|
14/01/2013
|
|
Date ISRCTN assigned
|
06/04/2000
|
