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Multicentre aneurysm screening study
DOI 10.1186/ISRCTN37381646
ClinicalTrials.gov identifier
EudraCT number
Public title Multicentre aneurysm screening study
Scientific title
Acronym MASS
Serial number at source G9533930
Study hypothesis To assess the effect of ultrasound screening for abdominal aortic aneurysm (AAA) on mortality from ruptured AAA.
Lay summary Not provided at time of registration
Ethics approval Not provided at time of registration
Study design Randomised controlled trial
Countries of recruitment United Kingdom
Disease/condition/study domain Cardiovascular
Participants - inclusion criteria Men aged 65-74 years on GP lists
Participants - exclusion criteria 1. Died before randomisation
2. Incorrect patient demographics
Anticipated start date 17/02/1997
Anticipated end date 16/02/2007
Status of trial Completed
Patient information material
Target number of participants 66,000
Interventions Ultrasound screening/control
Primary outcome measure(s) 1. Mortality for ruptured AAA as detected through the ONS and overall mortality
2. Cost effectiveness of screening for AAA and its effect on quality of life
Secondary outcome measure(s) Not provided at time of registration
Sources of funding Medical Research Council (MRC) (UK)
Trial website
Publications 1. 2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17502630
2. 2009 results in http://www.ncbi.nlm.nih.gov/pubmed/19553269
3. 2012 results in http://www.ncbi.nlm.nih.gov/pubmed/23034729
Contact name Mr  RAP  Scott
  Address Scott Research Unit
St Richard's Hospital
Spitalfield Lane
  City/town Chichester
  Zip/Postcode PO19 4SE
  Country United Kingdom
Sponsor Medical Research Council (MRC) (UK)
  Address 20 Park Crescent
  City/town London
  Zip/Postcode W1B 1AL
  Country United Kingdom
  Tel +44 (0)20 7636 5422
  Fax +44 (0)20 7436 6179
  Email clinical.trial@headoffice.mrc.ac.uk
  Sponsor website: http://www.mrc.ac.uk
Date applied 06/04/2000
Last edited 14/01/2013
Date ISRCTN assigned 06/04/2000
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