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ISRCTN
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ISRCTN35919612
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ClinicalTrials.gov identifier
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Public title
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Maintenance therapy in patients with severe Systemic lupus erythematosus (SLE): The BILAG multi-centre open randomised controlled trial comparing cyclosporin A and azathioprine
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Scientific title
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Acronym
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CYAZ
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Serial number at source
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G0535
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Systemic lupus erythematosus (SLE)
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Participants - inclusion criteria
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1. American Rheumatism Association (ARA) criteria for SLE
2. New corticosteroid sparing agent required
3. Patient on 15 mg or more of prednisolone for at least 4 weeks
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/06/1998
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Anticipated end date
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31/12/2004
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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1. Steroids tapered accordingly to protocol
2. Randomised to azathioprine or cyclosporin A
3. Dose increased according to body weight and tolerability
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Arthritis Research Campaign (UK)
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Trial website
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Publications
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Contact name
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Dr
Bridget
Griffiths
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Address
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Musculoskeletal Unit
Level 2 Freeman Hospitals
High Heaton
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City/town
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Newcastle upon Tyne
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Zip/Postcode
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NE7 7DN
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Country
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United Kingdom
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Tel
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+44 (0)191 284 3111
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Email
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bridget.griffiths@ncl.ac.uk
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Sponsor
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Arthritis Research Campaign (ARC) (UK)
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Address
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Copeman House
St Mary's Court
St Mary's Gate
Chesterfield
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City/town
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Derbyshire
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Zip/Postcode
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S41 7TD
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Country
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United Kingdom
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Email
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info@arc.org.uk
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Sponsor website:
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http://www.arc.org.uk
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Date applied
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18/07/2002
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Last edited
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28/04/2008
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Date ISRCTN assigned
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18/07/2002
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