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ISRCTN
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ISRCTN29775286
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ClinicalTrials.gov identifier
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Public title
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The effect of rofecoxib on colorectal liver metastases
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Scientific title
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Acronym
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N/A
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Serial number at source
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CRC COX2
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Study hypothesis
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Colorectal cancer, liver metastases
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Participants - inclusion criteria
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1. Age greater than or equal to 18 years
2. Either sex
3. Liver resection deemed clinically appropriate for management of metastatic Colorectal Cancer (CRC) liver disease
4. Duration between decision to perform liver resection and surgery greater than 2 weeks
5. Ability to give written informed consent
6. Telephone at home
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/01/1998
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Anticipated end date
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05/01/2002
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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1. Rofecoxib 25 mg/day
2. Placebo
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Merck and Co Inc. (USA)
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Trial website
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Publications
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2003 results in http://www.ncbi.nlm.nih.gov/pubmed/12949718
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Contact name
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Dr
-
-
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Address
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UKCCCR Register Co-ordinator
MRC Clinical Trials Unit
222 Euston Road
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City/town
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London
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Zip/Postcode
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NW1 2DA
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Country
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United Kingdom
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Tel
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+44 (0) 20 7670 4723
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Fax
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+44 (0) 20 7670 4818
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Email
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register@ctu.mrc.ac.uk
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Sponsor
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Cancer Research UK (CRUK) (UK)
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Address
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PO Box 123
Lincoln's Inn Fields
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City/town
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London
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Zip/Postcode
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WC2A 3PX
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Country
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United Kingdom
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Tel
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+44 (0)20 7317 5186
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Fax
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+44 (0)20 7487 4302
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Email
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kate.law@cancer.org.uk
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Sponsor website:
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http://www.cancer.org.uk
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Date applied
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01/07/2001
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Last edited
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21/11/2008
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Date ISRCTN assigned
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01/07/2001
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