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ISRCTN
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ISRCTN27270911
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ClinicalTrials.gov identifier
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Public title
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Advance care planning in advanced cancer - can it be achieved? A patient preference trial of a care planning discussion
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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1. What is the acceptability and feasibility of a patient preference randomised controlled trial of an intervention to facilitate planning for end-of-life care?
2. Which outcomes are appropriate and measurable to assess the effectiveness of this intervention?
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Lay summary
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Not provided at time of registration
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Ethics approval
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Royal Free Hospital and Medical School Local Research Ethics Committee. Approved on 17.08.06, ref 06/Q501/93
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Study design
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Randomised controlled patient preference trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Cancer
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Participants - inclusion criteria
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1. Have completed a primary course of treatment and still have clinically detectable, progressive, active disease
2. Are considered by the referring health professional to be well enough to complete the advance care planning discussion
3. Are over 18 years of age
4. Are able to give informed consent
5. Do not have psychotic illness
6. Speak and understand English (able to complete the questionnaires/interview)
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Participants - exclusion criteria
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1. Have not completed a primary course of treatment and still have clinically detectable, progressive, active disease
2. Are not considered by the referring health professional to be well enough to complete the advance care planning discussion
3. Are under 18 years of age
4. Are unable to give informed consent
5. Have psychotic illness
6. Do not speak and understand English (able to complete the questionnaires/interview)
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Anticipated start date
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15/01/2007
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Anticipated end date
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07/07/2008
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Status of trial
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Completed |
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Patient information material
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Not available in web format, please use the contact details below to request a patient information sheet
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Target number of participants
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100
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Interventions
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The intervention will consist of a one-to-one discussion with a trained mediator using a checklist of topic domains. Discussions will take place usually in participants' homes and last no more than one hour. Participants will be offered up to two further sessions with the mediator, to take place at a time of their choice. Discussions will be audio-taped and transcribed to examine the range and development of topics covered, how these change with time, and to ensure that the advisor has covered each domain as appropriate.
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Primary outcome measure(s)
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Change in scores on visual analogue scales measuring ability to discuss end-of-life planning with primary and secondary care professionals and close persons/members of the family
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Secondary outcome measure(s)
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1. Completion of an advance directive
2. Psychological status
3. Satisfaction with care
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Sources of funding
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Dimbleby Cancer Care (United Kingdom)
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Trial website
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Publications
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1. 2011 results in http://www.ncbi.nlm.nih.gov/pubmed/21352613
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Contact name
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Dr
Louise
Jones
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Address
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Marie Curie Palliative Care Research Unit
Royal Free and University College Medical School
Hampstead Campus
Rowland Hill Street
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City/town
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London
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Zip/Postcode
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NW3 2PF
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Country
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United Kingdom
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Email
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l.jones@medsch.ucl.ac.uk
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Sponsor
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University College London (UK)
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Address
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Gower Street
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City/town
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London
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Zip/Postcode
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WC1E 6BT
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Country
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United Kingdom
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Email
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o.avwenagha@medsch.ucl.ac.uk
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Sponsor website:
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http://www.ucl.ac.uk/
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Date applied
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08/01/2007
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Last edited
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05/01/2012
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Date ISRCTN assigned
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16/02/2007
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