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ISRCTN
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ISRCTN27244875
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ClinicalTrials.gov identifier
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Public title
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Randomised comparison of anticoagulation control and monitoring with versus without laboratory-provided computerized decision support
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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Laboratory-provided computerized decision support will improve anticoagulation control relative to usual care
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Lay summary
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Ethics approval
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Yes, August 2001
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Study design
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Cluster-randomised controlled trial
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Countries of recruitment
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Canada
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Disease/condition/study domain
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Various
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Participants - inclusion criteria
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Physicians:
1. Family or general practitioner
2. Full-time office practice
3. Practice address within study laboratory catchment area
4. At least 3 eligible patients willing to participate
Patients:
1. On long-term warfarin therapy
2. Using the study laboratory for international normalized ratio (INR) tests and expecting to continue to do so for at least 12 months
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Participants - exclusion criteria
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None
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Anticipated start date
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01/01/2002
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Anticipated end date
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30/06/2003
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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Physicians: 40; Patients: 380
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Interventions
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Anticoagulation control and monitoring with versus without laboratory-provided computerized decision support (CDS)
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Primary outcome measure(s)
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1. Acceptability of the CDS service, as assessed by the proportion of physicians who would continue to use it if offered
2. Estimated effectiveness, as assessed by percentage of time within target INR range
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Secondary outcome measure(s)
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Hemorrhagic and thromboembolic events requiring hospital attendance
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Sources of funding
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Ontario Program for Optimal Therapeutics (Canada)
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Trial website
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Publications
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Contact name
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Mr
Michael
Paterson
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Address
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ICES
G106-2075 Bayview Ave.
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City/town
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Toronto, Ontario
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Zip/Postcode
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M4N 3M5
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Country
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Canada
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Sponsor
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Ontario Program for Optimal Therapeutics (Canada)
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Address
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105 Main Street E, Level One
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City/town
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Hamilton, Ontario
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Zip/Postcode
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L8N 1G6
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Country
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Canada
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Date applied
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08/11/2005
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Last edited
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14/09/2009
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Date ISRCTN assigned
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25/11/2005
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