|
ISRCTN
|
ISRCTN25782645
|
|
ClinicalTrials.gov identifier
|
|
|
Public title
|
A randomised, double-blind, negatively-controlled study to determine whether the use of creams or ointments could alter the sensitivity of the skin to ultraviolet light during photo-therapy with narrow band UVB
|
|
Scientific title
|
|
|
Acronym
|
N/A
|
|
Serial number at source
|
N0547127254
|
|
Study hypothesis
|
Do creams or ointments applied before irradiation of the skin with narrow band UVB impair or improve the transmission of ultraviolet radiation to the skin?
|
|
Lay summary
|
Not provided at time of registration
|
|
Ethics approval
|
Not provided at time of registration
|
|
Study design
|
Randomised, double-blind, negatively-controlled study
|
|
Countries of recruitment
|
United Kingdom
|
|
Disease/condition/study domain
|
Not Applicable: Phototherapy
|
|
Participants - inclusion criteria
|
Not provided at time of registration
|
|
Participants - exclusion criteria
|
Not provided at time of registration
|
|
Anticipated start date
|
03/03/2003
|
|
Anticipated end date
|
31/05/2006
|
|
Status of trial
|
Completed |
|
Patient information material
|
|
|
Target number of participants
|
20 patients
|
|
Interventions
|
Creams or ointments applied before irradiation vs standard practice
|
|
Primary outcome measure(s)
|
Determination of MED in each subject for each topical agent at 24 hours after narrow band UVB exposure.
|
|
Secondary outcome measure(s)
|
Adverse events: pain, blistering, hyperpigmentary changes.
|
|
Sources of funding
|
East Norfolk and Waveney Research Consortium - Norfolk and Norwich University Hospital/Norwich PCT (UK)
|
|
Trial website
|
|
|
Publications
|
2011 results in http://www.ncbi.nlm.nih.gov/pubmed/20969563
|
|
Contact name
|
Dr
Eunice
Tan
|
|
Address
|
Department of Dermatology
Norfolk and Norwich University Hospital NHS Trust
Colney Lane
|
|
City/town
|
Norwich
|
|
Zip/Postcode
|
NR4 7UY
|
|
Country
|
United Kingdom
|
|
Email
|
|
|
Sponsor
|
Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
|
|
Address
|
The Department of Health,
Richmond House,
79 Whitehall
|
|
City/town
|
London
|
|
Zip/Postcode
|
SW1A 2NL
|
|
Country
|
United Kingdom
|
|
Tel
|
+44 (0)20 7307 2622
|
|
Email
|
dhmail@doh.gsi.org.uk
|
|
Sponsor website:
|
http://www.dh.gov.uk/Home/fs/en
|
|
Date applied
|
30/09/2004
|
|
Last edited
|
01/11/2011
|
|
Date ISRCTN assigned
|
30/09/2004
|
