Welcome
Support Centre
24 April 2014 
ISRCTN Register - International Standard Randomized Controlled Trial Number
Trial registration
Unique identification scheme
International databases
home  |   my details  |   ISRCTN Register  |   mRCT  |   links  |   information  |   news
Find trials
ISRCTN Register
tips on searching

Registration
New application
Updating record

Information
introduction
governing board
ISRCTN FAQs
data set
letter of agreement
request information
guidance notes
statistics

[ Print-friendly version ]
Evaluation of weight reduction programmes in the "Lighten Up" service in South Birmingham primary care trust (PCT)
ISRCTN ISRCTN25072883
DOI 10.1186/ISRCTN25072883
ClinicalTrials.gov identifier
EudraCT number
Public title Evaluation of weight reduction programmes in the "Lighten Up" service in South Birmingham primary care trust (PCT)
Scientific title Evaluation of weight reduction programmes in the "Lighten Up" service in South Birmingham primary care trust (PCT): a randomised controlled trial
Acronym Lighten Up
Serial number at source Version 4
Study hypothesis The weight loss programmes (Weight Watchers®, Slimming World, Rosemary Conley, NHS Size Down, pharmacy and general practice provision) will each achieve significantly greater weight loss at 3 months follow-up than the comparison group of exercise at a leisure centre. There will be no differences between the weight loss services in weight loss at 3 months.
Lay summary Not provided at time of registration
Ethics approval South Birmingham Research Ethics Committee, approved on 19/12/2008 (ref: 08/H1207/331)
Study design Randomised controlled trial
Countries of recruitment United Kingdom
Disease/condition/study domain Obesity
Participants - inclusion criteria 1. Aged at least 18 years, both males and females
2. Body mass index greater than or equal to 30 (based on data recorded via NHS Quality and Outcomes Framework [QoF])
3. Identified by GP as medically competent to enter the programme evaluation
Participants - exclusion criteria 1. Unable to understand English
2. Women who are known to be pregnant
3. Not willing to be randomised
Anticipated start date 26/01/2009
Anticipated end date 03/01/2011
Status of trial Completed
Patient information material Not available in web format, please use the contact details below to request a patient information sheet
Target number of participants 740
Interventions Participants will be allocated to one of the following eight arms:
1. Commercial weight loss programme: Weight Watchers
2. Commercial weight loss programme: Slimming World
3. Commercial weight loss programme: Rosemary Conley
4. Size Down (NHS community-based group programme)
5. Pharmacy-led obesity services
6. General practice service
7. Choice of intervention (1 to 6 above)
8. Comparator: Exercise advice + membership to leisure centre (Participants in this group will not be provided with any specific exercise programme)

Total duration of interventions: 12 weeks
Primary outcome measure(s) Weight at 3 months follow-up
Secondary outcome measure(s) 1. Weight loss at 1 year
2. Self-reported physical activity using the International Physical Activity Questionnaire-Short version (IPAQ-Short) at 3 and 12 months
3. Percentage weight loss at 3 months and 1 year
Sources of funding NHS South Birmingham (UK)
Trial website
Publications 1. 2011 results in http://www.ncbi.nlm.nih.gov/pubmed/22053315
Contact name Dr  Kate  Jolly
  Address Unit of Public Health, Epidemiology and Biostatistics
Public Health Building
University of Birmingham
Edgbaston
  City/town Birmingham
  Zip/Postcode B15 2TT
  Country United Kingdom
  Tel +44 (0)121 414 7552
  Email c.b.jolly@bham.ac.uk
Sponsor NHS South Birmingham (UK)
  Address c/o Dr Jim O'Brien
Head of Clinical Governance
8th Floor
Triplex House
Eckersall Road
Kings Norton
  City/town Birmingham
  Zip/Postcode B38 8SS
  Country United Kingdom
  Sponsor website: http://www.southbirminghampct.nhs.uk/
Date applied 19/01/2009
Last edited 20/12/2011
Date ISRCTN assigned 06/03/2009
Submit your trial protocol
Submit to Trials journal
Follow us on Twitter
© 2014 ISRCTN unless otherwise stated.