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ISRCTN
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ISRCTN21931925
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ClinicalTrials.gov identifier
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Public title
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Test of the open artery hypothesis
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Scientific title
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Acronym
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N/A
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Serial number at source
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PG/97051
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Study hypothesis
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Effect on ventricular modelling of angioplasty and stenting of the occluded infarct related artery (IRA) among patients with their first Q wave anterior myocardial infarction.
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Cardiovascular disease
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Participants - inclusion criteria
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Patients with Thrombolysis in Myocardial Infarction (TIMI) grade 0 or I.
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Participants - exclusion criteria
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Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
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Anticipated start date
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01/03/1997
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Anticipated end date
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01/06/1999
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Status of trial
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Completed
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Patient information material
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Target number of participants
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Not provided at time of registration
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Interventions
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Angiography and angioplasty carried out within 28 days of the acute event. Patients to be randomised into intervention or non-intervention groups.
Patients with TIMI grade II or III in the IRA or multi-vessel disease will be excluded.
Remaining patients with TIMI grade 0 or I will be randomised to intervention plus optimal medical therapy or optimal medical therapy alone.
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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British Heart Foundation (UK) (ref: PG/97051)
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Trial website
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Publications
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Results in http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12225709
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Contact name
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Dr
MS
Marber
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Address
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Dept of Cardiology
The Rayne Institute
St Thomas' Hospital
Lambeth Palace Road
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City/town
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London
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Zip/Postcode
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SE1 7EH
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Country
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United Kingdom
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Tel
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+44 (0)20 7836 5454
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Email
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mike.marber@kcl.ac.uk
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Sponsor
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British Heart Foundation (UK)
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Address
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14 Fitzhardinge Street
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City/town
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London
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Zip/Postcode
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W1H 6DH
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Country
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United Kingdom
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Tel
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+44 (0)20 7935 0185
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Fax
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+44 (0)20 7486 5820
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Email
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research@bhf.org.uk
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Sponsor website:
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http://www.bhf.org.uk/
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Date applied
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31/10/2001
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Last edited
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02/10/2007
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Date ISRCTN assigned
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31/10/2001
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