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ISRCTN
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ISRCTN21676344
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ClinicalTrials.gov identifier
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Public title
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Randomised, controlled trial of N-acetylcysteine for treatment of acute exacerbations of chronic obstructive pulmonary disease.
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Scientific title
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Acronym
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N/A
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Serial number at source
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N/A
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Study hypothesis
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Not provided at time of registration
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Lay summary
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Ethics approval
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Not provided at time of registration
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Study design
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Randomised controlled trial
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Countries of recruitment
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New Zealand
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Disease/condition/study domain
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Chronic obstructive pulmonary disease
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Participants - inclusion criteria
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Patients admitted to hospital with an acute exacerbation of chronic obstructive pulmonary disease.
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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01/06/2001
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Anticipated end date
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01/10/2001
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Status of trial
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Completed |
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Patient information material
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Target number of participants
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50
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Interventions
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N-acetylcysteine 600 mg twice daily or matching placebo.
All participants received standard care including oxygen, nebulised salbutamol, oral prednisone and antibiotics (if indicated).
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Primary outcome measure(s)
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Not provided at time of registration
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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Health Research Council of New Zealand (ref: HRC 01/206)
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Trial website
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Publications
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Results in http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15581425
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Contact name
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Dr
Peter
Black
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Address
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Department of Medicine
University of Auckland
Private Bag 92019
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City/town
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Auckland
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Zip/Postcode
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1001
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Country
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New Zealand
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Tel
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+64 93737599 ext 89797
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Fax
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+64 93677146
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Email
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pn.black@auckland.ac.nz
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Sponsor
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Health Research Council of New Zealand
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Address
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PO Box 5541
Wellesley St
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City/town
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Auckland
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Zip/Postcode
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1001
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Country
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New Zealand
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Tel
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+64 93035200
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Fax
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+64 93779988
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Email
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info@hrc.govt.nz
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Sponsor website:
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http://www.hrc.govt.nz/
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Date applied
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29/11/2004
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Last edited
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03/08/2007
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Date ISRCTN assigned
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30/11/2004
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