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ISRCTN
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ISRCTN18842004
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ClinicalTrials.gov identifier
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Public title
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A pilot study to determine the effects of corticotrophin releasing hormone (CRH) on myocardial function
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Scientific title
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Acronym
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N/A
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Serial number at source
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N0295132800
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Study hypothesis
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What is the effect of a single intravenous dose of CRH on myocardial contractility in normal, healthy subjects?
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Lay summary
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Not provided at time of registration
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Ethics approval
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Not provided at time of registration
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Study design
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Double blind randomised crossover pilot study
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Countries of recruitment
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United Kingdom
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Disease/condition/study domain
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Cardiovascular: Myocardial function
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Participants - inclusion criteria
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Healthy men or women, 18-60 years of age.
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Participants - exclusion criteria
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Not provided at time of registration
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Anticipated start date
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08/12/2003
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Anticipated end date
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30/04/2004
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Status of trial
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Completed |
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Patient information material
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Not available in web format, please use the contact details below to request a patient information sheet
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Target number of participants
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10 in total
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Interventions
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Single intravenous dose of CRH
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Primary outcome measure(s)
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Changes in measure of cardiac contractility/function as assessed by echocardiography: ejection fraction, fractional shortening, stroke volume, diastolic left ventricular filling, myocardial velocity, strain rate and strain.
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Secondary outcome measure(s)
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Not provided at time of registration
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Sources of funding
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University Hospitals Coventry and Warwickshire NHS Trust (UK)
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Trial website
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Publications
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Contact name
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Dr
Harpal
Randeva
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Address
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Metabolic Unit
Coventry & Warwickshire Hospital
Stoney Stanton Road
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City/town
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Coventry
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Zip/Postcode
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CV1 4FH
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Country
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United Kingdom
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Tel
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+44 (0)2476 844091/572552
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Fax
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+44 (0)2476 844118
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Email
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harpal.randeva@uhcw.nhs.uk
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Sponsor
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Record Provided by the NHSTCT Register - 2004 Update - Department of Health (UK)
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Address
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The Department of Health,
Richmond House,
79 Whitehall
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City/town
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London
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Zip/Postcode
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SW1A 2NL
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Country
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United Kingdom
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Tel
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+44 (0)20 7307 2622
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Email
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dhmail@doh.gsi.org.uk
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Sponsor website:
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http://www.dh.gov.uk/Home/fs/en
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Date applied
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30/09/2004
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Last edited
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22/11/2011
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Date ISRCTN assigned
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30/09/2004
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